Issue 37, 2022

Nanoscale patterning of polymers on DNA origami

Abstract

The combination of DNA–origami and synthetic polymers paves the way to a new class of structurally precise biohybrid nanomaterials for diverse applications. Herein, we introduce the grafting to method with high conversions (70–90%) under ambient conditions to generate DNA–polymer conjugates, which can hybridized precisely to DNA–origami architectures. We generated homo and block copolymers from three different polymer families (acrylates, methacrylates and acrylamides), coupled them to single stranded DNA (ssDNA) and pattern different DNA–origami architectures to demonstrate the formation of precise surface nanopatterns.

Graphical abstract: Nanoscale patterning of polymers on DNA origami

Supplementary files

Article information

Article type
Communication
Submitted
13 4 2022
Accepted
04 6 2022
First published
08 6 2022
This article is Open Access
Creative Commons BY license

J. Mater. Chem. B, 2022,10, 7512-7517

Nanoscale patterning of polymers on DNA origami

N. Alleva, P. Winterwerber, C. J. Whitfield, D. Y. W. Ng and T. Weil, J. Mater. Chem. B, 2022, 10, 7512 DOI: 10.1039/D2TB00812B

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