Issue 4, 2021

Flow biocatalysis 101: design, development and applications

Abstract

The integration of enzyme-catalyzed reactions in flow systems has been boosted during the last few years. Nowadays, biocatalysis is officially recognized as a tool to increase reaction specificity and sustainability, however applications are sometimes characterized by low productivity. A logical step to improve the performance of biocatalytic reactions is represented by the combination of enzymes and flow facilities. This tutorial review aims at introducing the key concepts of flow biocatalysis, guiding the reader through its advantages and highlighting the current trends in the field to encourage innovative applications of enzymes in flow reactors. Experimental cases are also presented and discussed as a troubleshooting guide for development of flow biocatalytic processes.

Graphical abstract: Flow biocatalysis 101: design, development and applications

Article information

Article type
Review Article
Submitted
22 12 2020
Accepted
03 2 2021
First published
03 2 2021
This article is Open Access
Creative Commons BY-NC license

React. Chem. Eng., 2021,6, 599-611

Flow biocatalysis 101: design, development and applications

A. I. Benítez-Mateos, M. L. Contente, D. Roura Padrosa and F. Paradisi, React. Chem. Eng., 2021, 6, 599 DOI: 10.1039/D0RE00483A

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