Issue 57, 2021

A review on phytochemical constituents and pharmacological potential of Calotropis procera

Abstract

Calotropis procera is locally known as Aak or Madar in Hindi, milk weed in English and belongs to the family Apocynaceae and subfamily Asclepiadoideae. Although a wasteland plant, it is of sacred use as its flowers are offered for worshipping Lord Shiva, a Hindu God. Tribes all over the world use the plant in treatment of various diseases like snake bite, body pain, asthma, epilepsy, cancer, sexual disorders, skin diseases and many more. This plant contains various phytoconstituents such as flavonoids, terpenoids, cardenolides, steroids oxypregnanes etc. Though literature searches reveal many reviews about ethnomedicinal uses, chemical composition and pharmacological activities, no recent papers are available that provide an overview of the therapeutic potential and toxicity of Calotropis procera. Hence, the insight of this review is to provide a systemic summary of phytochemistry, pharmacology, toxicology and therapeutic potential of Calotropis procera and to highlight the gaps in the knowledge so as to offer inspiration for future research.

Graphical abstract: A review on phytochemical constituents and pharmacological potential of Calotropis procera

Article information

Article type
Review Article
Submitted
06 9 2021
Accepted
25 10 2021
First published
04 11 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 35854-35878

A review on phytochemical constituents and pharmacological potential of Calotropis procera

B. D. Wadhwani, D. Mali, P. Vyas, R. Nair and P. Khandelwal, RSC Adv., 2021, 11, 35854 DOI: 10.1039/D1RA06703F

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