Issue 53, 2021

Synthesis of indole derivatives as prevalent moieties present in selected alkaloids

Abstract

Indoles are a significant heterocyclic system in natural products and drugs. They are important types of molecules and natural products and play a main role in cell biology. The application of indole derivatives as biologically active compounds for the treatment of cancer cells, microbes, and different types of disorders in the human body has attracted increasing attention in recent years. Indoles, both natural and synthetic, show various biologically vital properties. Owing to the importance of this significant ring system, the investigation of novel methods of synthesis have attracted the attention of the chemical community. In this review, we aim to highlight the construction of indoles as a moiety in selected alkaloids.

Graphical abstract: Synthesis of indole derivatives as prevalent moieties present in selected alkaloids

Article information

Article type
Review Article
Submitted
06 8 2021
Accepted
10 9 2021
First published
15 10 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 33540-33612

Synthesis of indole derivatives as prevalent moieties present in selected alkaloids

M. M. Heravi, Z. Amiri, K. Kafshdarzadeh and V. Zadsirjan, RSC Adv., 2021, 11, 33540 DOI: 10.1039/D1RA05972F

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