Issue 48, 2021

Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications

Abstract

Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient gene and drug delivery, controlled release and effective intracellular uptake, natural biodegradability in an acidic medium, and negligible toxicity. In this review, we study potential applications of LDH-based nanocomposite scaffolds for tissue engineering. We address how LDHs provide new solutions for nanostructure stability and enhance in vivo studies' success.

Graphical abstract: Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications

Article information

Article type
Review Article
Submitted
22 5 2021
Accepted
31 8 2021
First published
09 9 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 30237-30252

Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications

B. Izbudak, B. Cecen, I. Anaya, A. K. Miri, A. Bal-Ozturk and E. Karaoz, RSC Adv., 2021, 11, 30237 DOI: 10.1039/D1RA03978D

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