Issue 7, 2019

Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

Abstract

Fluoroalkylated alkynes, which are versatile building blocks for the synthesis of various biologically active organofluorine compounds, were synthesized from easily available alkynyl halides and fluoroalkyl halides by visible-light photocatalysis. Addition of fluoroalkyl radicals to alkynes and subsequent dehalogenation selectively yielded fluoroalkylated alkynes.

Graphical abstract: Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

Supplementary files

Article information

Article type
Communication
Submitted
06 10 2018
Accepted
06 11 2018
First published
07 11 2018

Org. Biomol. Chem., 2019,17, 1758-1762

Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

N. Iqbal, N. Iqbal, S. S. Han and E. J. Cho, Org. Biomol. Chem., 2019, 17, 1758 DOI: 10.1039/C8OB02486C

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