Issue 13, 2018

A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

Abstract

After a serendipitous synthesis of a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas, a more reliable synthetic method is now described using our building blocks containing stereodefined stereochemistry at C-20.

Graphical abstract: A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

Supplementary files

Article information

Article type
Research Article
Submitted
03 4 2018
Accepted
09 5 2018
First published
11 5 2018

Org. Chem. Front., 2018,5, 2016-2019

A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

H. Santalla, F. Garrido, G. Gómez and Y. Fall, Org. Chem. Front., 2018, 5, 2016 DOI: 10.1039/C8QO00338F

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