Issue 59, 2018
From the journal:

Chemical Communications

NaI-mediated divergent synthesis of isatins and isoindigoes: a new protocol enabled by an oxidation relay strategy†

Hong-hua Zhang,‡a   Yong-qiang Wang,‡a   Long-tao Huang,a   Long-qing Zhu,a   Yi-yue Feng,a   Ying-mei Lu,a   Quan-yi Zhao,a   Xue-qiang Wang ORCID logo *b  and  Zhen Wang ORCID logo *a  

* Corresponding authors

a School of Pharmacy, Lanzhou University, West Donggang Road. No. 199, Lanzhou 730000, China
E-mail: zhenw@lzu.edu.cn

b State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, 2 Lushan Nan Road, Changsha, Hunan 410082, China
E-mail: wangxq@hnu,edu.cn

Abstract

A new approach for the synthesis of isatins and isoindigoes by an inexpensive and environmentally friendly NaI-mediated transformation is disclosed. The selectivity could be switched by simply varying the solvent, and isatins (using THF) and isoindigoes (using DMSO) could be obtained in moderate to excellent yields.

Graphical abstract: NaI-mediated divergent synthesis of isatins and isoindigoes: a new protocol enabled by an oxidation relay strategy

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8CC04471F
Article type
Communication
Submitted
05 6 2018
Accepted
03 7 2018
First published
04 7 2018

Chem. Commun., 2018,54, 8265-8268

Permissions

Request permissions

NaI-mediated divergent synthesis of isatins and isoindigoes: a new protocol enabled by an oxidation relay strategy

H. Zhang, Y. Wang, L. Huang, L. Zhu, Y. Feng, Y. Lu, Q. Zhao, X. Wang and Z. Wang, Chem. Commun., 2018, 54, 8265 DOI: 10.1039/C8CC04471F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements