Issue 14, 2016

One-step ligand exchange and switching from hydrophobic to water-stable hydrophilic superparamagnetic iron oxide nanoparticles by mechanochemical milling

Abstract

We describe a simple, rapid methodology for the synthesis of water-stable iron oxide nanoparticles (IONPs) compatible with a variety of aqueous buffers, based on mechanochemical milling exchange of covalently bound surface ligands on pre-fabricated oleic acid-protected IONPs. Application of milling for IONP ligand exchange eliminates steps required for transforming hydrophobic into negatively charged, water-soluble superparamagnetic IONPs.

Graphical abstract: One-step ligand exchange and switching from hydrophobic to water-stable hydrophilic superparamagnetic iron oxide nanoparticles by mechanochemical milling

Supplementary files

Article information

Article type
Communication
Submitted
24 8 2015
Accepted
11 1 2016
First published
11 1 2016
This article is Open Access
Creative Commons BY license

Chem. Commun., 2016,52, 3054-3057

One-step ligand exchange and switching from hydrophobic to water-stable hydrophilic superparamagnetic iron oxide nanoparticles by mechanochemical milling

K. V. Korpany, C. Mottillo, J. Bachelder, S. N. Cross, P. Dong, S. Trudel, T. Friščić and A. S. Blum, Chem. Commun., 2016, 52, 3054 DOI: 10.1039/C5CC07107K

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements