Issue 23, 2015

Surface-immobilised micelles via cucurbit[8]uril-rotaxanes for solvent-induced burst release

Abstract

The fabrication, characterisation and controlled burst release of naphthol-functionalised micellar (NFM) nanostructures, which were grafted onto gold surfaces through cucurbit[8]uril (CB[8]) mediated host–guest interactions are described. NFMs undergo a facile change in morphology from micelles to diblock copolymers in direct response to exposure to organic solvents, including tetrahydrofuran (THF), toluene and chloroform. This induced transition in conformation lends itself to potential applications including nanocarriers for triggered burst-release of guest molecules. Nile Red was investigated as a NFM encapsulated model hydrophobic cargo inside the surface-attached micelles, which could be fully released upon exposure to THF as measured by both atomic force microscopy and UV/vis spectroscopy.

Graphical abstract: Surface-immobilised micelles via cucurbit[8]uril-rotaxanes for solvent-induced burst release

Supplementary files

Article information

Article type
Communication
Submitted
07 1 2015
Accepted
09 2 2015
First published
11 2 2015
This article is Open Access
Creative Commons BY license

Chem. Commun., 2015,51, 4858-4860

Surface-immobilised micelles via cucurbit[8]uril-rotaxanes for solvent-induced burst release

C. Hu, Y. Zheng, Z. Yu, C. Abell and O. A. Scherman, Chem. Commun., 2015, 51, 4858 DOI: 10.1039/C5CC00121H

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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