Issue 5, 2014

Trienamine catalysis with linear deconjugated 3,5-dienones

Abstract

An array of deconjugated linear 3,5-dienones with substantial substitutions have been successfully used in β,ε-regioselective Diels–Alder cycloadditions with 3-olefinic oxindole-based dienophiles via trienamine catalysis of cinchona-based primary amines, efficiently producing spirocyclic oxindole architectures with dense and diverse substitutions in high stereoselectivity (up to 99% ee, >19 : 1 d.r.).

Graphical abstract: Trienamine catalysis with linear deconjugated 3,5-dienones

Supplementary files

Article information

Article type
Research Article
Submitted
19 3 2014
Accepted
29 3 2014
First published
01 4 2014

Org. Chem. Front., 2014,1, 490-493

Author version available

Trienamine catalysis with linear deconjugated 3,5-dienones

P. Chen, Y. Xiao, C. Yue and Y. Chen, Org. Chem. Front., 2014, 1, 490 DOI: 10.1039/C4QO00079J

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