Issue 12, 2004

The single-step synthesis of a DNA tetrahedron

Abstract

A tetrahedral nanostructure whose edges are DNA double helices self-assembles spontaneously when four appropriately designed oligonucleotides are annealed together in solution; the ease of synthesis, rigidity, and adaptability of this construct make it a promising candidate as a cage for other large molecules and as a building block for more complicated nanostructures.

Graphical abstract: The single-step synthesis of a DNA tetrahedron

Supplementary files

Article information

Article type
Communication
Submitted
16 2 2004
Accepted
05 4 2004
First published
20 5 2004

Chem. Commun., 2004, 1372-1373

The single-step synthesis of a DNA tetrahedron

R. P. Goodman, R. M. Berry and A. J. Turberfield, Chem. Commun., 2004, 1372 DOI: 10.1039/B402293A

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