Issue 14, 2024

An overview of 6-shogaol: new insights into its pharmacological properties and potential therapeutic activities

Abstract

Ginger (Zingiber officinale Roscoe) has traditionally been used as a cooking spice and herbal medicine for treating nausea and vomiting. More recently, ginger was found to effectively reduce the risk of diseases such as gastroenteritis, migraine, gonarthritis, etc., due to its various bioactive compounds. 6-Shogaol, the pungent phenolic substance in ginger, is the most pharmacologically active among such compounds. The aim of the present study was to review the pharmacological characteristic of 6-shogaol, including the properties of anti-inflammatory, antioxidant and antitumour, and its corresponding molecular mechanism. With its multiple mechanisms, 6-shogaol is considered a beneficial natural compound, and therefore, this review will shed some light on the therapeutic role of 6-shogaol and provide a theoretical basis for the development and clinical application of 6-shogaol.

Graphical abstract: An overview of 6-shogaol: new insights into its pharmacological properties and potential therapeutic activities

Article information

Article type
Review Article
Submitted
31 10 2023
Accepted
07 1 2024
First published
08 1 2024

Food Funct., 2024,15, 7252-7270

An overview of 6-shogaol: new insights into its pharmacological properties and potential therapeutic activities

C. Yang, W. Chen, B. Ye and K. Nie, Food Funct., 2024, 15, 7252 DOI: 10.1039/D3FO04753A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements