Issue 18, 2022

A carboxylatopillar[5]arene-based pH-triggering supramolecular photosensitizer for enhanced photodynamic antibacterial efficacy

Abstract

A pH-triggering supramolecular antibacterial photosensitizer was constructed by host–guest interaction between a water-soluble porphyrin photosensitizer and carboxylatopillar[5]arene (P[5]). The formation of the supramolecular complex not only improves the biocompatibility of the photosensitizer, but also enhances antibacterial efficacy by pH-triggering dissociation under the low pH bacterial microenvironment.

Graphical abstract: A carboxylatopillar[5]arene-based pH-triggering supramolecular photosensitizer for enhanced photodynamic antibacterial efficacy

Supplementary files

Article information

Article type
Communication
Submitted
29 10 2021
Accepted
19 1 2022
First published
21 1 2022

Chem. Commun., 2022,58, 2991-2994

A carboxylatopillar[5]arene-based pH-triggering supramolecular photosensitizer for enhanced photodynamic antibacterial efficacy

T. Yue, L. Xia, J. Tian, B. Huang, C. Chen, H. Cao and W. Zhang, Chem. Commun., 2022, 58, 2991 DOI: 10.1039/D1CC06116J

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