Issue 6, 2014

Preparation of core–shell Fe3O4@poly(dopamine) magnetic nanoparticles for biosensor construction

Abstract

Novel core–shell Fe3O4@poly(dopamine) magnetic nanoparticles were prepared through an in situ self-polymerization method. The hybrid nanomaterial showed an average core diameter of 11 ± 3 nm and a polymer thin film thickness of 1.8 ± 0.2 nm. The core–shell nanoparticles were employed as solid supports for the covalent immobilization of horseradish peroxidase (HRP), and the resulting biofunctionalized magnetic nanoparticles were employed to construct an amperometric biosensor for H2O2. The enzyme biosensor showed a high sensitivity of 442.14 mA M−1 cm−2, a low limit of detection of 182 nM, a wide linear range from 6.0 × 10−7 to 8.0 × 10−4 M and high stability for 1 month.

Graphical abstract: Preparation of core–shell Fe3O4@poly(dopamine) magnetic nanoparticles for biosensor construction

Supplementary files

Article information

Article type
Paper
Submitted
21 8 2013
Accepted
21 11 2013
First published
25 11 2013

J. Mater. Chem. B, 2014,2, 739-746

Preparation of core–shell Fe3O4@poly(dopamine) magnetic nanoparticles for biosensor construction

M. Martín, P. Salazar, R. Villalonga, S. Campuzano, J. M. Pingarrón and J. L. González-Mora, J. Mater. Chem. B, 2014, 2, 739 DOI: 10.1039/C3TB21171A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements