Themed collection Journal of Materials Chemistry B Emerging Investigators
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Contributors to the Journal of Materials Chemistry B Emerging Investigators 2023 collection
Journal of Materials Chemistry B profiles contributors to the Emerging Investigators issue.
J. Mater. Chem. B, 2023,11, 9048-9055
https://doi.org/10.1039/D3TB90150E
Recent advances in double network hydrogels based on naturally-derived polymers: synthesis, properties, and biological applications
This review highlights recently developed double network hydrogels containing naturally-derived polymers, including discussion of synthetic methods, mechanical properties, and biological applications.
J. Mater. Chem. B, 2023,11, 11460-11482
https://doi.org/10.1039/D3TB00773A
Rational design and engineering of polypeptide/protein vesicles for advanced biological applications
The rational design and engineering strategies, employed in polypeptide/protein vesicles, from synthesis to assembly, for advanced biological and medical applications.
J. Mater. Chem. B, 2023,11, 8834-8847
https://doi.org/10.1039/D3TB01103H
Beyond traditional light: NIR-II light-activated photosensitizers for cancer therapy
This review focuses on the recent progress of various NIR-II photosensitizers for photodynamic therapy, and briefly presents the ongoing challenges and prospects of NIR-II photosensitizers for clinical translation.
J. Mater. Chem. B, 2023,11, 8315-8326
https://doi.org/10.1039/D3TB00668A
Control of charge transport in electronically active systems towards integrated biomolecular circuits (IbC)
Crafting integrated biomolecular circuits (IbC) via self-assembly of electronically active molecules using a “bottom-up” paradigm provides a potential solution to the technological challenges of the miniaturization of silicon-based electronics.
J. Mater. Chem. B, 2023,11, 8302-8314
https://doi.org/10.1039/D3TB00701D
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Tuning foreign body response with tailor-engineered nanoscale surface modifications: fundamentals to clinical applications
The synergistic effect of nanotopography and chemistry in modulating different stages of the foreign body response, impacting cell–protein–biomaterial interactions.
J. Mater. Chem. B, 2023,11, 7834-7854
https://doi.org/10.1039/D3TB01040F
Rational design and combinatorial chemistry of ionizable lipids for RNA delivery
This review will delve into the crucial role of ionizable lipids in the development of lipid nanoparticles (LNPs) for efficient RNA delivery.
J. Mater. Chem. B, 2023,11, 6527-6539
https://doi.org/10.1039/D3TB00649B
AIEgens for synergistic anticancer therapy
To improve the precision of cancer treatment, maximize therapeutic effects, and minimize mortality, AIEgen-based synergistic therapies combining imaging technologies, phototherapy, and other therapies will be introduced and perspected in this review.
J. Mater. Chem. B, 2023,11, 5953-5975
https://doi.org/10.1039/D3TB00219E
Polymeric engineering of AIEgens for NIR-II fluorescence imaging and detection of abdominal metastases of ovarian cancer in vivo
Polymeric engineering of amphiphilic polymers used for NIR-II AIEgens encapsulation affords high-brightness AIEdots with small size and long blood circulation time, allowing improved fluorescence imaging in vivo.
J. Mater. Chem. B, 2023,11, 11217-11221
https://doi.org/10.1039/D3TB01750H
Engineering metabolic cycle-inspired hydrogels with enzyme-fueled programmable transient volume changes
The development of hydrogels that can exhibit a transient response, fueled by enzymes, while also depleting the enzymatic activity of fuel, holds immense potential for sophisticated materials capable of dynamically intervening in biological events.
J. Mater. Chem. B, 2023,11, 8136-8141
https://doi.org/10.1039/D3TB00638G
Redox-dual-sensitive multiblock copolymer vesicles with disulfide-enabled sequential drug delivery
A facile redox-controlled sequential delivery of hydrophilic and hydrophobic drugs was achieved by multiblock copolymer vesicles containing disulfide as the only kind of responsive linkage.
J. Mater. Chem. B, 2023,11, 2631-2637
https://doi.org/10.1039/D2TB02686D
Osteoimmune-modulating and BMP-2-eluting anodised 3D printed titanium for accelerated bone regeneration
3D printing of titanium (Ti) metal has potential to transform the field of personalised orthopaedics and dental implants.
J. Mater. Chem. B, 2024,12, 97-111
https://doi.org/10.1039/D3TB01029E
Manipulation of cross-linking in PEDOT:PSS hydrogels for biointerfacing
The effect of gelling agent concentration (ionic liquid) on PEDOT:PSS hydrogel fabrication and properties was investigated. Gelation kinetics, stability, swelling, stiffness, conductivity, and support of seeded cells were characterized.
J. Mater. Chem. B, 2023,11, 11357-11371
https://doi.org/10.1039/D3TB01415K
Chitosan functionalized gold nanostars as a theranostic platform for intracellular microRNA detection and photothermal therapy
A theranostic nanoplatform (AuNS@CS-hpDNA) was developed with chitosan-functionalized gold nanostars (AuNSs) and further complexed with hairpin DNA (hpDNA) probes for tumor-related miRNA imaging and photothermal therapy (PTT).
J. Mater. Chem. B, 2023,11, 11082-11093
https://doi.org/10.1039/D3TB02029K
Belinostat loaded lipid–polymer hybrid nanoparticulate delivery system for breast cancer: improved pharmacokinetics and biodistribution in a tumor model
A novel lipid polymer hybrid nanoparticulate system to improve the systemic exposure of Belinostat and aid in efficient tumor uptake.
J. Mater. Chem. B, 2023,11, 10859-10872
https://doi.org/10.1039/D3TB01317K
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Validation of transparent and flexible neural implants for simultaneous electrophysiology, functional imaging, and optogenetics
We developed and compared transparent micro electrocorticography arrays (μECoGs) to combine electrophysiology and functional imaging. PEDOT:PSS-based μECoGs had the best trade-off of material and physical properties for chronic in vivo experiments.
J. Mater. Chem. B, 2023,11, 9639-9657
https://doi.org/10.1039/D3TB01191G
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Remodeling arteries: studying the mechanical properties of 3D-bioprinted hybrid photoresponsive materials
A 3D-printed artery wall model that mimics arterial pulsation is reported where the expansion and contraction of thermoresponsive polymers through plasmonic nanoparticles results in the activation of mechanotransduction gene pathways.
J. Mater. Chem. B, 2023,11, 9431-9442
https://doi.org/10.1039/D3TB01480K
Photoactivated plasmonic nanohybrid fibers with prolonged trapping of excited charge carriers for SERS analysis of biomolecules
Pre-activation of SERS plasmonic substrate with UV light leads to the creation of long-lived charged states resulting in better attachment of proteins and an increase in the SERS chemical enhancement.
J. Mater. Chem. B, 2023,11, 9212-9222
https://doi.org/10.1039/D3TB00980G
Dual enzyme-mimicking carbon dots for enhanced antibacterial activity
Carbon dot (CD)-based nanozymes have great potential in antibacterial applications through the design of the structure.
J. Mater. Chem. B, 2023,11, 8916-8925
https://doi.org/10.1039/D3TB01376F
Plasmonic alloys for quantitative determination and reaction monitoring of biothiols
Plasmonic alloys were designed to assist the laser desorption/ionization process in mass spectrometry, for quantitative determination and reaction monitoring of biothiols.
J. Mater. Chem. B, 2023,11, 8639-8648
https://doi.org/10.1039/D3TB01076G
NIR-II fluorescence and PA imaging guided activation of STING pathway in photothermal therapy for boosting cancer immunotherapy by theranostic thermosensitive liposomes
A versatile PLDD was developed with the light-triggered promotion of anti-tumor immunity and NIR-II fluorescence and PA imaging profiles, soaring the therapeutic effect and providing accurate spatiotemporal imaging for photothermal immunotherapy.
J. Mater. Chem. B, 2023,11, 8528-8540
https://doi.org/10.1039/D3TB00711A
A general method for endowing hydrophobic nanoparticles with water dispersion abilities
We have developed a generally applicable method involving using dimercaptosuccinic acid (DMSA) for endowing hydrophobic inorganic nanoparticles with water dispersion abilities.
J. Mater. Chem. B, 2023,11, 8464-8470
https://doi.org/10.1039/D2TB01038K
Two-dimensional TiO nanosheets with photothermal effects for wound sterilization
With high NIR light absorption and sharp nanosheet edges, TiO NSs have excellent mechanical and photothermal bactericidal properties, which is the only report to date on titanium-based oxides in wound healing.
J. Mater. Chem. B, 2023,11, 7641-7653
https://doi.org/10.1039/D3TB01170D
A nanoscale inorganic coating strategy for stabilizing hydrogel neural probes in vivo
Hydrogels with adaptable optical and mechanical characteristics show considerable promise for light delivery in vivo with neuroengineering applications.
J. Mater. Chem. B, 2023,11, 7629-7640
https://doi.org/10.1039/D3TB00710C
Hollow multishelled heterostructures with enhanced performance for laser desorption/ionization mass spectrometry based metabolic diagnosis
High-performance metabolic diagnosis-based laser desorption/ionization mass spectrometry (LDI-MS) improves the precision diagnosis of diseases and subsequent treatment.
J. Mater. Chem. B, 2023,11, 8206-8215
https://doi.org/10.1039/D3TB00766A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Polymyxin B stabilized DNA micelles for sustained antibacterial and antibiofilm activity against P. aeruginosa
DNA based micelles demonstrate high biofilm penetration and potential for antibiotic delivery.
J. Mater. Chem. B, 2023,11, 7972-7985
https://doi.org/10.1039/D3TB00704A
Soft, flexible conductivity sensors for ocean salinity monitoring
Soft, flexible conductivity sensors composed of gold electrodes are developed and characterized for real-time, corrosion-free ocean salinity measurements under optimized operation conditions (AC voltage of 0.6 V).
J. Mater. Chem. B, 2023,11, 7334-7343
https://doi.org/10.1039/D3TB01167D
Fluorination of naphthalimide–cyanostilbene derivatives to achieve dual-state emission luminogens with strong fluorescence in highly polar environments for bioimaging
Fluorination of naphthalimide–cyanostilbene derivatives to achieve dual-state emission luminogens with good environmental stability of fluorescence in solution and two-photon absorption (2PA) properties for cell-imaging with lipid droplet targeting.
J. Mater. Chem. B, 2023,11, 6859-6867
https://doi.org/10.1039/D3TB01034A
Phytantriol phase behaviour in choline chloride urea and water mixtures
Phytantriol forms a Pn3m cubic phase in both water and neat choline chloride:urea. However, mixtures of the DES with water result in phytantriol forming an inverse hexagonal phase and influenced phase transition temperatures.
J. Mater. Chem. B, 2023,11, 6868-6880
https://doi.org/10.1039/D3TB00554B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Marine-origin polysaccharides-based free-standing multilayered membranes as sustainable nanoreservoirs for controlled drug delivery
Free-standing (FS) membranes encompassing N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride (HTCC) and alginate (ALG) multilayers triggered a sustained release of FITC-BSA when incorporated as an intrinsic building block of the FS membranes.
J. Mater. Chem. B, 2023,11, 6671-6684
https://doi.org/10.1039/D3TB00796K
Nanozyme-integrated microneedle patch for enhanced therapy of cutaneous squamous cell carcinoma by breaking the gap between H2O2 self-supplying chemodynamic therapy and photothermal therapy
A microneedle patch has been developed to bridge the gap between H2O2 self-supplying chemodynamic therapy and photothermal therapy, resulting in enhanced therapy of cutaneous squamous cell carcinoma.
J. Mater. Chem. B, 2023,11, 6595-6602
https://doi.org/10.1039/D3TB00708A
A fluorinated ionizable lipid improves the mRNA delivery efficiency of lipid nanoparticles
The combination of ionizable lipids bearing alkyl chains and fluorinated alkyl chains improves the cellular uptake and mRNA expression of lipid nanoparticles.
J. Mater. Chem. B, 2023,11, 4171-4180
https://doi.org/10.1039/D3TB00516J
Inflammation-targeting polyamine nanomedicines for the treatment of ulcerative colitis
Orally administered anti-inflammatory polyamine-based nanomedicines are presented. Inflammation-targeting, radical scavenging, and biocompatible nanomedicines may serve as therapeutic drugs for inflammatory diseases.
J. Mater. Chem. B, 2023,11, 4005-4013
https://doi.org/10.1039/D3TB00424D
Photo-/piezo-activated ultrathin molybdenum disulfide nanomedicine for synergistic tumor therapy
In this study, based on energy-converting nanomedicine, we report multifunctional two-dimensional (2D) molybdenum disulfide (MoS2) nanosheets with an inherent plasmonic property and piezocatalytic activity for imaging-guided synergistic tumor therapy.
J. Mater. Chem. B, 2023,11, 2895-2903
https://doi.org/10.1039/D3TB00209H
About this collection
Journal of Materials Chemistry B is pleased to present this themed collection highlighting the rising stars of materials chemistry research in 2023. This special collection showcases the very best work from materials chemists in the early stages of their independent career.
Each contributor was recommended by experts in their fields as carrying out work with the potential to influence future directions in materials chemistry with applications in biology and medicine. Congratulations to all the outstanding researchers featured!
See also:
Journal of Materials Chemistry A Emerging Investigators 2023
Journal of Materials Chemistry C Emerging Investigators 2023