Hybrid nanoparticle composites
Jessica Winter, Julien Nicolas and Gang Ruan introduce the Journal of Materials Chemistry B themed issue on hybrid nanoparticle composites.
Cell membrane-engineered hybrid soft nanocomposites for biomedical applications
An overview of various cell membrane-engineered hybrid soft nanocomposites for medical applications.
Synthesis, modification and bioapplications of nanoscale copper chalcogenides
The recent advances in the synthesis, modification and bioapplications of nanoscale copper chalcogenides are comprehensively reviewed.
Gold nanoparticle-conjugated nanomedicine: design, construction, and structure–efficacy relationship studies
Recent studies on gold nanoparticle-conjugated nanomedicine are reviewed with a focus on design, construction, and structure–efficacy relationship studies.
Organic/inorganic nanohybrids rejuvenate photodynamic cancer therapy
This article reviewed the organic/inorganic hybrid nanoplatforms for improving the photodynamic therapeutic efficacy of cancers.
Advances and challenges in metallic nanomaterial synthesis and antibacterial applications
Schematic diagram of the antibacterial mechanism of metal nanoparticles.
Hybrid nanoparticle composites applied to photodynamic therapy: strategies and applications
Boosting PDT outcome through specialized nano-hybrids for achieving active tumor-targeting, remodeling tumor hypoxia, activating tumorous release, and facilitating deep penetration.
Tumor microenvironment-activated NIR-II reagents for tumor imaging and therapy
This review summarizes the recent advances of tumor microenvironment-activated NIR-II agents for tumor diagnosis and treatment, including smart NIR-II fluorescence imaging, photoacoustic imaging, photothermal therapy and photodynamic therapy.
Transition metal complexes as imaging or therapeutic agents for neurodegenerative diseases
Neurodegenerative diseases are the result of neurodegeneration, which is the process of losing neuronal functions gradually due to the irreversible damage and death of neurons. Metal complexes have attracted intense interest over recent decades as probes or inhibitors of biomolecules.
Communication
Light-switchable anchors on magnetized biomorphic microcarriers
Combining silica-biomorphs, magnetite mesocrystals and covalently bound spiropyrans into light-switchable microcarriers.
The in situ synthesis of silver nanoclusters inside a bacterial cellulose hydrogel for antibacterial applications
An antibacterial hydrogel is developed through in situ formation of Ag nanoclusters on bacterial cellulous, which shows better and longer-lasting killing efficacy than that of pristine Ag NCs against both Gram-positive and Gram-negative bacteria.
Hyaluronic acid functionalized gold nanorods combined with copper-based therapeutic agents for chemo-photothermal cancer therapy
Hyaluronic acid functionalized gold nanorods with loading of copper complexes show a unique release manner and synergetic antitumor efficacy.
Introduction of an antifouling photoelectrode: an effective strategy for a high-performance photoelectrochemical cytosensor
An efficient strategy for a high-performance PEC cytosensor with enhanced sensitivity and selectivity was proposed by introducing an antifouling photoelectrode for the first time.
Sensitive detection of clenbuterol by hybrid iridium/silicon nanowire-enhanced laser desorption/ionization mass spectrometry
Here we report the development of hybrid Ir/SiNW as a new MALDI matrix for potential anti-doping drug monitoring in sports and food safety checks.
Paper
Optimization of analytical assay performance of antibody-gated indicator-releasing mesoporous silica particles
An in-depth study of the chemical tuning modes of antibody-gated indicator delivery (gAID) systems revealed the importance of size matching, localisation of grafting and loading sequence for obtaining high-performance small-molecule sensor materials.
Ornithine-derived oligomers and dendrimers for in vitro delivery of DNA and ex vivo transfection of skin cells via saRNA
Ornithine dendrimers exhibit high activity as vectors for saRNA in cells and skin, highlighting their potential use in RNA vaccines.
Synthesis and characterisation of biocompatible organic–inorganic core–shell nanocomposite particles based on ureasils
A one-pot route to ureasil core–shell nanoparticles that exhibit low polydispersity, high stability and low cytotoxicity is reported.
Paper
Polymer-encapsulation of iron oxide clusters using macroRAFT block copolymers as stabilizers: tuning of the particle morphology and surface functionalization
We report a versatile platform for the preparation of magnetic carriers stabilized by macroRAFT amphiphilic block copolymers, exhibiting encapsulated morphologies, high iron oxide content and tailored surface functionalizations.
Plasmonic gel nanocomposites for detection of high energy electrons
The development of a plasmonic gel nanocomposite to detect therapeutic levels of high energy electrons is demonstrated.
Encapsulating insoluble antifungal drugs into oleic acid-modified silica mesocomposites with enhanced fungicidal activity
Oleic acid-modified silica mesocomposites as an insoluble antifungal drug cargo matrix with enhanced fungicidal activity.
Nanoengineering multifunctional hybrid interfaces using adhesive glycogen nanoparticles
Amphiphilic phytoglycogen nanoparticles are used as building blocks for engineering multifunctional hybrid films with catalytic and sensing properties.
Hybrid silver–gold nanoparticles suppress drug resistant polymicrobial biofilm formation and intracellular infection
Quercetin reduced hybrid silver–gold nanoparticles inhibit polymicrobial biofilm formation and intracellular infection.
Protein corona formation and its influence on biomimetic magnetite nanoparticles
Colloidal stability and cellular uptake of MamC-biomimetic magnetite nanoparticles (BMNPs) incubated with human plasma (PC-BMNPs).
Superhydrophobic highly flexible doubly cross-linked aerogel/carbon nanotube composites as strain/pressure sensors
We report novel superhydrophobic highly flexible composites based on a doubly cross-linked aerogel and carbon nanotubes for highly sensitive strain/pressure sensing.
pH-Sensitive nanotheranostics for dual-modality imaging guided nanoenzyme catalysis therapy and phototherapy
A theranostic nanosystem with a pH-sensitive structure showed charge conversion properties in the tumor acidic microenvironment. It could perform dual-modality imaging diagnosis and carry out catalysis therapy and phototherapy.
About this collection
Guest Edited by Jessica Winter, The Ohio State University, Julien Nicolas, Institut Galien Paris-Sud, and Gang Ruan, Nanjing University.
As synthesis of individual nanoparticles has advanced, nanoparticles are increasingly combined with other materials into composites for specific applications. These hybrid materials are often multifunctional, preserving capabilities of their individual constituents, or consist of components with disparate properties, such as organic/inorganic or hydrophobic/hydrophilic sub-units. Materials can be passive or dynamic, with responses such as conformation change or degradation triggered by particular cues. Different components are combined to achieve multiple, and/or altered, and/or new functions. Hybrid nanoparticle composites have great promise in healthcare, agricultural, and environmental applications.
This Themed Issue aims to explore the latest developments in materials design and synthesis, novel design and function of hybrid nanoparticle composites, and their potential applications for healthcare, biotechnology, and environmental applications.