Themed collection Frontiers in Stimuli-Responsive Nanoplatforms: Pioneering Drug Delivery in Nanobiotechnology

14 items
Open Access Editorial

Frontiers in stimuli-responsive nanoplatforms: pioneering drug delivery in nanobiotechnology

Prof. Juan C. Cruz and Prof. Luis H. Reyes introduce the Nanoscale Advances themed issue on Frontiers in Stimuli-Responsive Nanoplatforms: Pioneering Drug Delivery in Nanobiotechnology.

Graphical abstract: Frontiers in stimuli-responsive nanoplatforms: pioneering drug delivery in nanobiotechnology
Open Access Review Article

Strategies for enhanced gene delivery to the central nervous system

Biological barriers in the central nervous system.

Graphical abstract: Strategies for enhanced gene delivery to the central nervous system
From the themed collection: Recent Review Articles
Open Access Communication

Dual-color core–shell silica nanosystems for advanced super-resolution biomedical imaging

Tailored synthesis and biotin-functionalization of dual-colored SiO2 nanoparticles as tools for advanced super-resolution microscopy imagining in biomedical approaches.

Graphical abstract: Dual-color core–shell silica nanosystems for advanced super-resolution biomedical imaging
Open Access Paper

Preparation of a minocycline polymer micelle thermosensitive gel and its application in spinal cord injury

Neuroprotection is an important approach for the treatment of spinal cord injury (SCI).

Graphical abstract: Preparation of a minocycline polymer micelle thermosensitive gel and its application in spinal cord injury
Open Access Paper

Effects of silver-decorated PLGA nanoparticles on Staphylococcus epidermidis biofilms and evaluation of the detoxification limit of bacteria against these nanoparticles

Silver nanoparticles exhibit high antibacterial activity and thus have been used in polymeric formulations for drug delivery.

Graphical abstract: Effects of silver-decorated PLGA nanoparticles on Staphylococcus epidermidis biofilms and evaluation of the detoxification limit of bacteria against these nanoparticles
Open Access Paper

Unraveling the impact of different liposomal formulations on the plasma protein corona composition might give hints on the targeting capability of nanoparticles

Investigating complex patterns in the plasma protein corona of different liposomal formulations to identify formulation-specific protein clusters which in turn may suggest possible targeting capability.

Graphical abstract: Unraveling the impact of different liposomal formulations on the plasma protein corona composition might give hints on the targeting capability of nanoparticles
Open Access Paper

Long-term in vivo dissolution of thermo- and pH-responsive, 19F magnetic resonance-traceable and injectable polymer implants

Thermo- and pH-responsive polymers' dissolution in vivo can be broadly fine-tuned. Polymeric implant can be detected in vivo using “hot-spot” 19F MR measurement. Long-term in vivo dissolution of polymeric implant shows no side effects.

Graphical abstract: Long-term in vivo dissolution of thermo- and pH-responsive, 19F magnetic resonance-traceable and injectable polymer implants
Open Access Paper

In vitro profiling and molecular dynamics simulation studies of berberine loaded MCM-41 mesoporous silica nanoparticles to prevent neuronal apoptosis

Berberine-loaded mesoporous silica nanoparticle-controlled drug release by a simple or quasi-diffusion mechanism, improving neuronal health, preventing apoptosis, and restoring mitochondrial membrane potential.

Graphical abstract: In vitro profiling and molecular dynamics simulation studies of berberine loaded MCM-41 mesoporous silica nanoparticles to prevent neuronal apoptosis
Open Access Paper

Probing the pH-dependency of DC-SIGN/R multivalent lectin–glycan interactions using polyvalent glycan-gold nanoparticles

DC-SIGN displays distinct pH-dependent binding with GNP-DiMan, strong tetravalent binding to single GNP-DiMan at pH 7.4, weak crosslinking at pH 5.4, and no apparent binding at pH 4.6, consistent with its biological role as an endocytic recycling receptor.

Graphical abstract: Probing the pH-dependency of DC-SIGN/R multivalent lectin–glycan interactions using polyvalent glycan-gold nanoparticles
Open Access Paper

Bioelectrochemically triggered apoferritin-based bionanoreactors: synthesis of CdSe nanoparticles and monitoring with leaky waveguides

Enzymatic processes, specifically laccase (Lac) catalysis, control molecular or nanomaterial synthesis within apoferritin by inducing a local pH change. Leaky waveguides technique is used for real-time monitoring of CdSe nanoparticles synthesis.

Graphical abstract: Bioelectrochemically triggered apoferritin-based bionanoreactors: synthesis of CdSe nanoparticles and monitoring with leaky waveguides
Open Access Paper

A new vision of photothermal therapy assisted with gold nanorods for the treatment of mammary cancers in adult female rats

Graphical abstract showing the whole photothermal process assisted with gold nanoparticles in female rats.

Graphical abstract: A new vision of photothermal therapy assisted with gold nanorods for the treatment of mammary cancers in adult female rats
Open Access Paper

Surfactant-driven optimization of iron-based nanoparticle synthesis: a study on magnetic hyperthermia and endothelial cell uptake

This work examines the effect of changing the ratio of different surfactants in single-core iron-based nanoparticles in the context of magnetic hyperthermia and cellular uptake by human umbilical vein endothelial cells.

Graphical abstract: Surfactant-driven optimization of iron-based nanoparticle synthesis: a study on magnetic hyperthermia and endothelial cell uptake
Open Access Paper

Synthesis of a light-responsive platinum curcumin complex, chemical and biological investigations and delivery to tumor cells by means of polymeric nanoparticles

The combination of chemical synthesis and nanotechnology led to the creation of a powerful multifunctional drug delivery system for a new platinum curcumin complex.

Graphical abstract: Synthesis of a light-responsive platinum curcumin complex, chemical and biological investigations and delivery to tumor cells by means of polymeric nanoparticles
Open Access Paper

Light-initiated aggregation of gold nanoparticles for synergistic chemo-photothermal tumor therapy

The combination of chemotherapy with photothermal therapy (PTT) has attracted extensive attention due to its excellent synergetic effect attributing to the fact that hyperthermia can effectively promote the tumor uptake of chemotherapeutic drugs.

Graphical abstract: Light-initiated aggregation of gold nanoparticles for synergistic chemo-photothermal tumor therapy
14 items

About this collection

Guest Edited by Prof. Juan C. Cruz and Prof. Luis H. Reyes (Universidad de los Andes, Colombia). This collection focuses on the recent developments and novel approaches in stimuli-responsive nanoplatforms for drug delivery. Papers highlight the design, synthesis, and application of these nanoplatforms, with an emphasis on their potential to transform therapeutic delivery methods. We aim to highlight the intersection of nanobiotechnology and drug delivery, fostering discussions on future trends and challenges within this exciting field.

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