Fifth International Symposium on Metallomics 2015
Guest editors Chunying Chen, Zhifang Chai and Xinrong Zhang introduce this themed issue showcasing work from the Fifth International Symposium on Metallomics 2015.
Probing the molecular mechanism of cerium oxide nanoparticles in protecting against the neuronal cytotoxicity of Aβ1–42 with copper ions
The molecular mechanism of CeONPs in protecting against neuronal cytotoxicity from amyloid peptides and copper ions was investigated systematically by photoluminescence of [Ru(phen)2dppz]2+, morphology of TEM, mass spectroscopy, cell viability assay, ROS fluorescence assay, and EPR.
Integration of fluorescence imaging with proteomics enables visualization and identification of metallo-proteomes in living cells
“Metal-tunable” fluorescent probe for tracking and editing metalloproteomes inside living cells.
MicroXRF tomographic visualization of zinc and iron in the zebrafish embryo at the onset of the hatching period
Synchrotron-based X-ray fluorescence microtomography offers new insights into the three-dimensional distribution of zinc and iron at a key stage of zebrafish embryogenesis.
Asplatin enhances drug efficacy by altering the cellular response
Asplatin, the conjugate of aspirin and cisplatin, promotes cell apoptosis by highly efficient activation of the BCL-2 associated mitochondrial pathway.
Paper
Elemental bioimaging and speciation analysis for the investigation of Wilson's disease using μXRF and XANES
A liver biopsy specimen of a Wilson's disease patient was analyzed by means of micro-X-ray fluorescence (μXRF) and X-ray absorption near edge structure spectroscopy (XANES).
The association of depressed angiogenic factors with reduced capillary density in the Rhesus monkey model of myocardial ischemia
Copper loss in ischemic myocardium makes a critical contribution to the suppression of HIF-1-regulated angiogenesis.
Comparative metalloproteomic approaches for the investigation proteins involved in the toxicity of inorganic and organic forms of mercury in rice (Oryza sativa L.) roots
The toxicity mechanisms of rice roots under inorganic mercury (IHg) or methylmercury (MeHg) stress were investigated using metalloproteomic approaches.
About this collection
This is a collection of papers highlighting the work presented at the 5th International Conference on Metallomics, September 9-12, 2015, Beijing, China. Guest Edited by Professors Chunying Chen, Xingrong Zhang and Zhifang Chai. New articles will be added to this collection as they are published.