Personalized protein corona on nanoparticles and its clinical implications
It is increasingly being accepted that the protein corona is strongly affected by the patient's specific disease. Therefore, the same nanomaterial incubated with plasma proteins of patients with different pathologies adsorb protein coronas with different compositions, giving rise to the concept of personalized protein corona.
Bioinks for 3D bioprinting: an overview
Bioprinting is an emerging technology with various applications in making functional tissue constructs to replace injured or diseased tissues. In all bioprinting strategies, the bioinks are an essential component. We provide an in-depth discussion of the different bioinks currently employed for bioprinting, and outline some future perspectives in their further development.
Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO)
Potential biomedical applications of nitric oxide (NO) releasing polymers.
Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery
Galectin8-GFP cytosolic redistribution to bright puncta serve as sensor for LNP escape from endosomal compartments.
Milk exosomes with enhanced mucus penetrability for oral delivery of siRNA
High-purity milk exosomes were engineered with surface PEGylation and siRNA encapsulation for enhanced oral drug delivery.
Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver
High-throughput in vivo screening identified several LNPs formulated with DOPE that preferentially accumulated in the liver, while identical LNPs formulated with DSPC preferentially accumulated in the spleen.
Clickable PEG hydrogel microspheres as building blocks for 3D bioprinting
Clickable poly(ethylene glycol) hydrogel microspheres can be 3D printed and photochemically annealed to produce complex cell-laden structures.
Intracellular delivery and biodistribution study of CRISPR/Cas9 ribonucleoprotein loaded bioreducible lipidoid nanoparticles
A combinatorial library of cationic lipidoids were used as nanocarriers for intracellular delivery of the CRISPR/Cas9 ribonucleoprotein complex.
Paper
Injectable dynamic covalent hydrogels of boronic acid polymers cross-linked by bioactive plant-derived polyphenols
Wisdom from nature: Plant-derived polyphenolic compounds can crosslink boronic acid functionalized polymers through formation of dynamic covalent bonds and function as both cross-linker and bioactive cargo.
In vitro and in vivo analysis of visible light crosslinkable gelatin methacryloyl (GelMA) hydrogels
Engineering visible light crosslinked GelMA hydrogels with tunable physical properties.
Effects of ovalbumin protein nanoparticle vaccine size and coating on dendritic cell processing
Nanoparticle vaccine delivery platforms are a promising technology for enhancing vaccine immunogenicity.
Media additives to promote spheroid circularity and compactness in hanging drop platform
Three-dimensional spheroid cultures have become increasingly popular as drug screening platforms, especially with the advent of different high throughput spheroid forming technologies.
Gelatin hydrogels formed by orthogonal thiol–norbornene photochemistry for cell encapsulation
Gelatin-norbornene was synthesized for preparing cytocompatible and tunable covalent gelatin hydrogels via an orthogonal step-growth thiol–ene photoclick reaction.
Magnetic iron oxide–fluorescent carbon dots integrated nanoparticles for dual-modal imaging, near-infrared light-responsive drug carrier and photothermal therapy
The multifunctional hybrid nanoparticles described demonstrate great promise towards advanced nanoplatforms for simultaneous imaging diagnostics and high efficacy therapy.
3D printed tricalcium phosphate bone tissue engineering scaffolds: effect of SrO and MgO doping on in vivo osteogenesis in a rat distal femoral defect model
SrO and MgO doped 3D printed tricalcium phosphate scaffolds showed accelerated osteogenesis through increased bone formation and accelerated mineralization.
About this collection
This online collection features some of the most cited, most downloaded and most shared articles from North America published in Biomaterials Science during the first 10 years of the journal.
Congratulations to all the authors whose articles are featured and thank you to all our authors, reviewers and readers for your ongoing support.