Issue 3, 2017
From the journal:

Inorganic Chemistry Frontiers

AIEgen-functionalised mesoporous silica nanoparticles as a FRET donor for monitoring drug delivery†

Duo Wang,a   Jie Chen,b   Li Ren,a   Qinglan Li,a   Dongdong Li*c  and  Jihong Yu*a  

* Corresponding authors

a State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, P. R. China
E-mail: jihong@jlu.edu.cn

b Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, P. R. China

c Department of Materials Science, Jilin University, Changchun 130012, P. R. China
E-mail: lidongdong@jlu.edu.cn

Abstract

Aggregation-induced emission luminogens (AIEgens), tetraphenylethene, were post grafted onto mesoporous silica nanoparticles to form AIEgen-functionalised mesoporous materials. The obtained blue-emitting materials can serve as a fluorescence resonance energy transfer (FRET) donor for monitoring the release process of doxorubicin hydrochloride (DOX) as an acceptor by the change of the fluorescent signal, showing potential application in imaging-guided therapy.

Graphical abstract: AIEgen-functionalised mesoporous silica nanoparticles as a FRET donor for monitoring drug delivery

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Article information

DOI
https://doi.org/10.1039/C6QI00488A
Article type
Research Article
Submitted
07 11 2016
Accepted
31 12 2016
First published
03 1 2017

Inorg. Chem. Front., 2017,4, 468-472

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AIEgen-functionalised mesoporous silica nanoparticles as a FRET donor for monitoring drug delivery

D. Wang, J. Chen, L. Ren, Q. Li, D. Li and J. Yu, Inorg. Chem. Front., 2017, 4, 468 DOI: 10.1039/C6QI00488A

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