Issue 62, 2015
From the journal:

Chemical Communications

A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria†

Guangxue Feng,ab   Youyong Yuan,a   Hu Fang,c   Ruoyu Zhang,a   Bengang Xing,d   Guanxin Zhang,c   Deqing Zhang*c  and  Bin Liu*ae  

* Corresponding authors

a Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore 117576, Singapore
E-mail: cheliub@nus.edu.sg
Fax: +65-6779-1936

b Environmental Research Institute, National University of Singapore, Singapore 117411, Singapore

c Beijing National Laboratory for Molecular Sciences, Organic Solids Laboratory, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
E-mail: dqzhang@iccas.ac.cn

d Division of Chemistry and Biological Chemistry, Nanyang Technological University, Singapore, Singapore

e Institute of Materials Research and Engineering, Institute of Materials Research Engineering (A*STAR), 3 Research Link, Singapore 117602, Singapore

Abstract

We report the design and synthesis of a red fluorescent AIE light-up probe for selective recognition, naked-eye detection, and image-guided photodynamic killing of Gram-positive bacteria, including vancomycin-resistant Enterococcus strains.

Graphical abstract: A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria

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Supplementary files

Article information

DOI
https://doi.org/10.1039/C5CC03807C
Article type
Communication
Submitted
07 5 2015
Accepted
22 6 2015
First published
22 6 2015

Chem. Commun., 2015,51, 12490-12493

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A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria

G. Feng, Y. Yuan, H. Fang, R. Zhang, B. Xing, G. Zhang, D. Zhang and B. Liu, Chem. Commun., 2015, 51, 12490 DOI: 10.1039/C5CC03807C

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