Binding assays enable discovery of Tet(X) inhibitors that combat tetracycline destructase resistance

Matthew J. Beech, Edmond C. Toma, Helen G. Smith, Maria M. Trush, Jit H. J. Ang, Mei Y. Wong, Chung H. J. Wong, Hafiz S. Ali, Zakia Butt, Viha Goel, Fernanda Duarte, Alistair J. M. Farley, Timothy R. Walsh and Christopher J. Schofield

Chem. Sci., 2025, 16, 9691
DOI: 10.1039/D5SC00964B

Specific variants in ftsI reduce carbapenem susceptibility in Pseudomonas aeruginosa

Hirokazu Yano, Noboru Nakata, Koji Yahara, Motoyuki Sugai, Yukari Sato and Daria Van Tyne

Microbiol Spectr, 2025, 13
DOI: 10.1128/spectrum.01027-25

Addressing antimicrobial resistance: Structural insights into cefiderocol’s mode of action and emerging resistance mechanisms

Mohd Zulkifli Salleh

Journal of Infection and Public Health, 2025, 18, 102871
DOI: 10.1016/j.jiph.2025.102871