OR2H2 Activates CAMKKβ–AMPK–Autophagy Signaling Axis and Suppresses Senescence in VK2/E6E7 Cells

Ji Min Kim, Sina Dziobaka, Ye Eun Yoon, Ha Lim Lee, Ji Hyun Jeong, In-Ryeong Lee, Daniel Weidinger, Changwon Yang, Deokho Kim, Yalcin Gulperi, Cheol-Koo Lee, Jeongwon Sohn, Gwonhwa Song, Hanns Hatt and Sung-Joon Lee

Pharmaceuticals, 2023, 16, 1221
DOI: 10.3390/ph16091221

Glutathione and glutathione-dependent enzymes: From biochemistry to gerontology and successful aging

Domenico Lapenna

Ageing Research Reviews, 2023, 92, 102066
DOI: 10.1016/j.arr.2023.102066

Tricin Delays Aging and Enhances Muscle Function via Activating AMPK-Mediated Autophagy in Diverse Model Organisms

Yun-Fei Zhu, Xing-Yue Zhou, Cai Lan, Yong-Ping Wen, Hai-Jun Fu, Zhi-Chao Li, Ya-Ping Li, Shi-Ying Li, Fei-Hong Huang, Long Wang, Lu Yu, Da-Lian Qin, An-Guo Wu, Jian-Ming Wu and Xiao-Gang Zhou

J. Agric. Food Chem., 2025, 73, 10246
DOI: 10.1021/acs.jafc.4c12619

Non-Genomic Hallmarks of Aging—The Review

Drahomira Holmannova, Pavel Borsky, Helena Parova, Tereza Stverakova, Milan Vosmik, Libor Hruska, Zdenek Fiala and Lenka Borska

IJMS, 2023, 24, 15468
DOI: 10.3390/ijms242015468

Resveratrol reduces RVLM neuron activity via activating the AMPK/Sirt3 pathway in stress-induced hypertension

Lin-Ping Wang, Tian-Feng Liu, Teng-Teng Dai, Xin Deng, Lei Tong, Qiang-Cheng Zeng, Qing He, Zhang-Yan Ren, Hai-Li Zhang, Hai-Sheng Liu, Yan-Fang Li, Wen-Zhi Li, Shuai Zhang and Dong-Shu Du

Journal of Biological Chemistry, 2025, 301, 108394
DOI: 10.1016/j.jbc.2025.108394

Downregulation of CD38, CD95, and PD-1 Expression in T Cells of Aging Mice by Intervention of Polygala fallax Hemsl

Yang Yang, Emmanuel P. Leaño, Y.-T. Yu, P.P. Piccaluga and S. Xie

BIO Web Conf., 2024, 111, 01002
DOI: 10.1051/bioconf/202411101002

Research progress of AMP-activated protein kinase and cardiac aging

Zhengqi Qiu, Yufei Li, Yancheng Fu and Yanru Yang

Open Life Sciences, 2023, 18
DOI: 10.1515/biol-2022-0710

Antiaging effects of dietary supplements and natural products

Lulu Gao, Xudong Liu, Xiaoyan Luo, Xiaofan Lou, Pusen Li, Xian Li and Xiaomeng Liu

Front. Pharmacol., 2023, 14
DOI: 10.3389/fphar.2023.1192714

The impact of a polyphenol-rich supplement on epigenetic and cellular markers of immune age: a pilot clinical study

Austin Perlmutter, Jeffrey S. Bland, Arti Chandra, Sonia S. Malani, Ryan Smith, Tavis L. Mendez and Varun B. Dwaraka

Front. Nutr., 2024, 11
DOI: 10.3389/fnut.2024.1474597

Advanced Delivery System of Polyphenols for Effective Cancer Prevention and Therapy

Koung Hee Kim, Mi-Ran Ki, Ki Ha Min and Seung Pil Pack

Antioxidants, 2023, 12, 1048
DOI: 10.3390/antiox12051048

A Reappraisal of the Antiviral Properties of and Immune Regulation through Dietary Phytochemicals

Mony Thakur, Mona Singh, Sandeep Kumar, Ved Prakash Dwivedi, Tikam Chand Dakal and Vinod Yadav

ACS Pharmacol. Transl. Sci., 2023, 6, 1600
DOI: 10.1021/acsptsci.3c00178

Cocoa shell ingredients improve their lipid-lowering properties under simulated digestion: In vitro and HepG2 cells study

Cheyenne Braojos, Miguel Rebollo-Hernanz, Silvia Cañas, Yolanda Aguilera, Alicia Gil-Ramírez, Vanesa Benítez and Maria A. Martín-Cabrejas

Food Research International, 2024, 196, 115037
DOI: 10.1016/j.foodres.2024.115037

In silico and in vitro studies reveal a synergistic potential source of novel anti-ageing from two Indonesian green algae

Fahrul Nurkolis, Athaya Febriantyo Purnomo, Darmawan Alisaputra, William Ben Gunawan, Faqrizal Ria Qhabibi, Woohee Park, Myunghan Moon, Nurpudji Astuti Taslim, Moon Nyeo Park and Bonglee Kim

Journal of Functional Foods, 2023, 104, 105555
DOI: 10.1016/j.jff.2023.105555

Anti-Aging Effect of Traditional Plant-Based Food: An Overview

Gitishree Das, Srinivasan Kameswaran, Bellamkonda Ramesh, Manjunatha Bangeppagari, Rajat Nath, Anupam Das Talukdar, Han-Seung Shin and Jayanta Kumar Patra

Foods, 2024, 13, 3785
DOI: 10.3390/foods13233785

Efficient glycosylation of polyphenols via dynamic complexation of cyclodextrin and synchronous coupling reaction with cyclodextrin glycosyltransferase in water

Jiaqi Ding, Xiaoxiao Li, Zhengyu Jin, Maher Abou Hachem and Yuxiang Bai

International Journal of Biological Macromolecules, 2024, 280, 136065
DOI: 10.1016/j.ijbiomac.2024.136065

Exploring Skin Longevity Pathways: Rosa hybrid Extract-Mediated AMP-Activated Protein Kinase Activation, Antioxidant, and Autophagic Mechanisms in Human Keratinocytes

Olivier Gouin, Andrea Cavagnino, Gayané Azadiguian, Sibylle Jäger, Gilles Comte, Mohammed Bendahmane, Lionel Breton, Martin A. Baraibar and Annie F. Black

Cosmetics, 2025, 12, 57
DOI: 10.3390/cosmetics12020057

TGF-β as A Master Regulator of Aging-Associated Tissue Fibrosis

Li-Li Ren, Hua Miao, Yan-Ni Wang, Fei Liu, Ping Li and Ying-Yong Zhao

Aging and disease, 2023, 14, 1633
DOI: 10.14336/AD.2023.0222

Polyphenol Compound 18a Modulates UCP1-Dependent Thermogenesis to Counteract Obesity

Xueping Wen, Yufei Song, Mei Zhang, Yiping Kang, Dandan Chen, Hui Ma, Fajun Nan, Yanan Duan and Jingya Li

Biomolecules, 2024, 14, 618
DOI: 10.3390/biom14060618

AMPK and metabolic disorders: The opposite roles of dietary bioactive components and food contaminants

Ye Peng, Zexiu Qi, Yuqing Xu, Xueyan Yang, Yue Cui and Quancai Sun

Food Chemistry, 2024, 437, 137784
DOI: 10.1016/j.foodchem.2023.137784

Impact of plant-derived antioxidants on heart aging: a mechanistic outlook

Muneer Ahmed Khoso, Heng Liu, Tong Zhao, Wenjie Zhao, Qiang Huang, Zeqi Sun, Khuzin Dinislam, Chen Chen, Lingyi Kong, Yong Zhang and Xin Liu

Front. Pharmacol., 2025, 16
DOI: 10.3389/fphar.2025.1524584

Natural polyphenols as novel interventions for aging and age-related diseases: Exploring efficacy, mechanisms of action and implications for future research

Wenze Wu, Yan Mi, Qingqi Meng, Ning Li, Wei Li, Pu Wang and Yue Hou

Chinese Herbal Medicines, 2025, 17, 279
DOI: 10.1016/j.chmed.2024.09.001

Changes of Signaling Pathways in Hypothalamic Neurons with Aging

Petr M. Masliukov

CIMB, 2023, 45, 8289
DOI: 10.3390/cimb45100523

Kaempferol: Paving the path for advanced treatments in aging-related diseases

Md Sadique Hussain, Abdulmalik Saleh Alfawaz Altamimi, Muhammad Afzal, Waleed Hassan Almalki, Imran Kazmi, Sami I. Alzarea, Gaurav Gupta, Moyad Shahwan, Neelima Kukreti, Ling Shing Wong, Vinoth Kumarasamy and Vetriselvan Subramaniyan

Experimental Gerontology, 2024, 188, 112389
DOI: 10.1016/j.exger.2024.112389

Impact of NF-κB Signaling and Sirtuin-1 Protein for Targeted Inflammatory Intervention

Sagar Das, Tuhin Mukherjee, Satyajit Mohanty, Nikita Nayak, Payel Mal, Sumel Ashique, Radheshyam Pal, Sourav Mohanto and Himanshu Sharma

CPB, 2025, 26, 1207
DOI: 10.2174/0113892010301469240409082212

Dog Aging: A Comprehensive Review of Molecular, Cellular, and Physiological Processes

Gabriella Guelfi, Camilla Capaccia, Martina Tedeschi, Antonello Bufalari, Leonardo Leonardi, Beniamino Cenci-Goga and Margherita Maranesi

Cells, 2024, 13, 2101
DOI: 10.3390/cells13242101

Oxymatrine Improves Oxidative Stress-Induced Senescence in HT22 Cells and Mice via the Activation of AMP-Activated Protein Kinase

Nagarajan Maharajan, Chang-Min Lee, Karthikeyan A. Vijayakumar and Gwang-Won Cho

Antioxidants, 2023, 12, 2078
DOI: 10.3390/antiox12122078

Supplementing Ryegrass Ameliorates Commercial Diet-Induced Gut Microbial Dysbiosis-Associated Spleen Dysfunctions by Gut–Microbiota–Spleen Axis

Qasim Ali, Sen Ma, Boshuai Liu, Jiakuan Niu, Mengqi Liu, Ahsan Mustafa, Defeng Li, Zhichang Wang, Hao Sun, Yalei Cui and Yinghua Shi

Nutrients, 2024, 16, 747
DOI: 10.3390/nu16050747

Molecular Mechanisms of Polyphenols in Management of Skin Aging

Deepti Dwevedi and Ankur Srivastava

CAS, 2024, 17, 180
DOI: 10.2174/0118746098287130240212085507

Mitochondria-targeted esculetin and metformin delay endothelial senescence by promoting fatty acid β-oxidation: Relevance in age-associated atherosclerosis

Sriravali Pulipaka, Hridya Chempon, Gajalakshmi Singuru, Shashikanta Sahoo, Altab Shaikh, Sunita Kumari, Rajamannar Thennati and Srigiridhar Kotamraju

Mechanisms of Ageing and Development, 2024, 219, 111931
DOI: 10.1016/j.mad.2024.111931

Investigating the Effects of Chelidonic Acid on Oxidative Stress-Induced Premature Cellular Senescence in Human Skin Fibroblast Cells

Burcu Turkoglu and Banu Mansuroglu

Life, 2024, 14, 1070
DOI: 10.3390/life14091070

Hydroxytyrosol Interference with Inflammaging via Modulation of Inflammation and Autophagy

Francesca Velotti and Roberta Bernini

Nutrients, 2023, 15, 1774
DOI: 10.3390/nu15071774

Long-stranded non-coding RNAs temporal-specific expression profiles reveal longissimus dorsi muscle development and intramuscular fat deposition in Tianzhu white yak

Zhaohua He, Xiangyan Wang, Youpeng Qi, Chune Zhu, Zhidong Zhao, Xiaolan Zhang, Xiu Liu, Shaobin Li, Fangfang Zhao, Jiqing Wang, Bingang Shi and Jiang Hu

Journal of Animal Science, 2023, 101
DOI: 10.1093/jas/skad394

Green Tea Polyphenol (-)-Epicatechin Pretreatment Mitigates Hepatic Steatosis in an In Vitro MASLD Model

Marija Hefer, Ana Petrovic, Lucija Kuna Roguljic, Tea Omanovic Kolaric, Tomislav Kizivat, Catherine H. Wu, Ashraf A. Tabll, Robert Smolic, Aleksandar Vcev and Martina Smolic

CIMB, 2024, 46, 8981
DOI: 10.3390/cimb46080531