Synthesis of lactones and lactams via C(sp3)–H bond functionalization

Egambaram Premkumar, Ramdas Sreedharan, Premananda Ghosh, Tanay Pal, Debabrata Maiti and Thirumanavelan Gandhi

Chem. Soc. Rev., 2025, 54, 6238
DOI: 10.1039/D4CS01152J

Iodoarene-directed photoredox β-C(sp3)–H arylation of 1-(o-iodoaryl)alkan-1-ones with cyanoarenes via halogen atom transfer and hydrogen atom transfer

Liang Zeng, Chong-Hui Xu, Xiu-Yuan Zou, Qing Sun, Ming Hu, Xuan-Hui Ouyang, De-Liang He and Jin-Heng Li

Chem. Sci., 2024, 15, 6522
DOI: 10.1039/D3SC06637A

Pd-catalyzed regioselective activation of C(sp2)–H and C(sp3)–H bonds

Wajid Ali, Gwyndaf A. Oliver, Daniel B. Werz and Debabrata Maiti

Chem. Soc. Rev., 2024, 53, 9904
DOI: 10.1039/D4CS00408F

Unified approaches in transition metal catalyzed C(sp3)–H functionalization: recent advances and mechanistic aspects

Jagrit Grover, Amal Tom Sebastian, Siddhartha Maiti, Alex C. Bissember and Debabrata Maiti

Chem. Soc. Rev., 2025, 54, 2006
DOI: 10.1039/D0CS00488J

Multistep Reactions Initiated by Amine‐Based Organometallic Methods

Victoria D. Ho, Olutayo N. Farinde, Kendra K. Shrestha and Michael C. Young

Eur J Org Chem, 2025
DOI: 10.1002/ejoc.202500607

Palladium-Catalyzed Annulations via Sequential C–H Activations of C(sp2)–H/C(sp3)–H or C(sp3)–H/C(sp3)–H Bonds

Wan-Xu Wei, Mateusz Czajkowski, Yangjin Kuang, Tu-Anh V. Nguyen, Bo Qin and Martin Tomanik

ACS Catal., 2024, 14, 6535
DOI: 10.1021/acscatal.4c01243

Catalytic Aerobic Carbooxygenation for the Construction of Vicinal Tetrasubstituted Centers: Application to the Synthesis of Hexasubstituted γ‐Lactones

Florian Pünner, Yoshihiro Sohtome, Yanzong Lyu, Daisuke Hashizume, Mai Akakabe, Mami Yoshimura, Yoko Yashiroda, Minoru Yoshida and Mikiko Sodeoka

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202405876

Catalytic Aerobic Carbooxygenation for the Construction of Vicinal Tetrasubstituted Centers: Application to the Synthesis of Hexasubstituted γ‐Lactones

Florian Pünner, Yoshihiro Sohtome, Yanzong Lyu, Daisuke Hashizume, Mai Akakabe, Mami Yoshimura, Yoko Yashiroda, Minoru Yoshida and Mikiko Sodeoka

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202405876

Ligand-Enabled Palladium-Catalyzed β-C(sp3)–H Biarylation of Native Amides with Cyclic Diaryliodonium Salts

Animesh Das, Mohit Chotia and Biplab Maji

Org. Lett., 2025, 27, 4997
DOI: 10.1021/acs.orglett.5c01313

Directed C(sp3)-H Arylation of Free α-Aminophosphonates: Dual Models Exploration via Palladium Catalysis

Li−Na Yi, Tao Zhao, Jinghan Bu, Jiedi Long and Qiang Yang

Org. Lett., 2024, 26, 4132
DOI: 10.1021/acs.orglett.4c01322

γ-Amino C(sp3)–H Functionalization of Aliphatic Amines through a Light-Driven Triple Catalysis

Masanari Nakagawa, Kazunori Nagao and Hirohisa Ohmiya

ACS Catal., 2024, 14, 8005
DOI: 10.1021/acscatal.4c02004

Palladium‐Catalyzed C(sp3)−H Activation in A Monoterpene‐Based Compound Under Mild Conditions: A Combined Experimental and Theoretical Mechanistic Study

Tatiana E. Kokina, Nikita A. Shekhovtsov, Alexey V. Tkachev, Alexander M. Agafontsev, Christophe Gourlaouen and Mark B. Bushuev

ChemPlusChem, 2025, 90
DOI: 10.1002/cplu.202400509

Tunable Preparation of β‐Substituted Alkenoate Esters via Radical Alkenylation of C(sp3)–H Bonds with Allenoates

Alexandra Jorea, Roberto Chessa and Davide Ravelli

Adv Synth Catal, 2025, 367
DOI: 10.1002/adsc.202500012

Transition-Metal-Catalyzed C(sp3)–H Bond Activation through Coordination-Assisted and Radical Mechanisms: Recent Advances and Mechanistic Insight

Mohammad Sadegh Karimtabar, Fatemeh Doraghi, Bagher Larijani and Mohammad Mahdavi

Top Curr Chem (Z), 2025, 383
DOI: 10.1007/s41061-025-00511-1

Ligand-Enabled Palladium(II)-Catalyzed γ-C(sp3)–H Arylation of Primary Aliphatic Amines

Chen-Hui Yuan and Lei Jiao

Org. Lett., 2024, 26, 29
DOI: 10.1021/acs.orglett.3c03186

Pd‐Catalyzed δ‐C(sp3)−H Thiolation of Amino Acid Derivatives

Andrés García‐Viada, Celia Sánchez‐González, Mario Martínez‐Mingo, Inés Alonso, Nuria Rodríguez and Juan C. Carretero

Adv Synth Catal, 2023, 365, 3973
DOI: 10.1002/adsc.202300808

The evolution of directing group strategies for C(sp)–H activation

Jayabrata Das, Wajid Ali and Debabrata Maiti

Trends in Chemistry, 2023, 5, 551
DOI: 10.1016/j.trechm.2023.05.003

Cu(I)-Catalyzed C(sp3)–H Functionalization of Amino Acids with Benzimidate and Reactive Oxygen Species (ROS) To Synthesize Triazines and 2-Pyrrolidinones

Subhasis Pal, Rajesh Nandi, Anindya S. Manna, Debanjana Bag, Rajjakfur Rahaman and Dilip K. Maiti

Org. Lett., 2024, 26, 9828
DOI: 10.1021/acs.orglett.4c03536