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A novel effective protocol towards indolo[2,1-a]isoquinolinones via aryne-induced migration of aryl-anion in aryloxy substituted 3,4-dihydroisoquinolines is reported. These novel 12a-aryl substituted indoxylisoquinolines exhibit fluorescence properties and are characterized by green-shifted spectra and moderate quantum yields.

Graphical abstract: Synthesis of novel fluorescent 12a-aryl substituted indoxylisoquinolines via aryne-induced domino process

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