Ana Sousa-Herves, Stefanie Wedepohl and Marcelo Calderón
Chem. Commun., 2015,51, 5264-5267
DOI:
10.1039/C5CC00644A,
Communication
Doxorubicin-loaded nanogels with multiresponsive properties are prepared using hyperbranched polyglycerol as a biocompatible scaffold. The nanogels are synthesized in a single step combining free-radical polymerization and a mild nanoprecipitation technique. The nanogels respond to different biological stimuli such as low pH and reductive environments, resulting in a more efficient cell proliferation inhibition in A549 cells.
