Advancements in nano-based drug delivery systems for therapeutics: a comprehensive review

Abstract

In contemporary medicine, nano-based drug delivery systems (NDDS) have become a ground-breaking strategy, offering notable improvements in the regulated and targeted release of medicinal drugs. These systems use nanotechnology to reduce adverse effects, increase therapeutic efficacy, and improve medication absorption. In order to achieve certain drug release patterns and improve patient outcomes, recent developments have focused on the creation and optimization of nanoparticles, liposomes, dendrimers, and micelles, among other materials. With an emphasis on advancements in materials, formulation techniques, and targeting mechanisms, this paper reviews current developments in NDDS. In addition to their challenges, such as toxicity, scaling issues, and regulatory barriers, the potential applications of NDDS in the future, such as gene therapy, customized medicine, and several drug delivery systems, are also reviewed. The development of nanotechnology for drug delivery has enormous potential to transform treatment paradigms in a number of therapeutic domains, such as infectious diseases, cancer, and chronic illnesses.