Continuous-flow synthesis of special Au–Ag bimetallic nanoparticles and their application for SERS detection of thiram in cherry juice

Abstract

Here, using quasi-spherical Ag nanoparticles (NPs) as intermediates, continuous-flow synthesis of special Au–Ag bimetallic nanoparticles is efficiently achieved. Meanwhile, the microstructure evolution of Au–Ag bimetallic NPs is revealed, providing a theoretical reference for the microstructure control of bimetallic NPs. Furthermore, these special Au–Ag bimetallic NPs exhibit excellent performance for the SERS detection of thiram in cherry juice, indicating significant application potential in food safety.