Artificial spidroin bioelectronic dressings for intelligent wound management

Wound infection has always been a huge threat to human health. Most of the existing wound medical materials are made of composite materials with poor biocompatibility and may contain harmful chemicals, which may cause allergic reactions and secondary wound infection, becoming a hidden danger to human health. Therefore, there is an urgent need to develop innovative medical materials for wound treatment. At present, the intelligent application of high-performance materials prepared from artificial spider silk protein (spidroin) in wound healing has been widely discussed. Its advantages are good biocompatibility, biodegradability, cell adhesion and excellent bioelectronic performance. In this paper, the biological application of various high-performance medical materials prepared from artificial spidroins in wound healing was introduced, and the sequence design and synthesis methods of artificial spidroins were briefly discussed. Finally, the application prospects of high-performance medical materials prepared from artificial spidroins in wound treatment are discussed.