This website uses cookies to give you the best user experience. If you continue without changing your settings we'll assume you are happy to receive all RSC cookies. You can change your cookie settings by navigating to our Privacy and Cookies page and following the instructions. These instructions are also obtainable from the privacy link at the bottom of any RSC page.
Lite Version|Standard version
Home > Chemical Communications >
To gain access to this content please
Log in via your home Institution.
Log in with your member or subscriber username and password.
Download


Buy PDF Add PDF to Basket (£42.50*)
*Exclusive of taxes
This article contains 4 page(s)
Abstract | Cited by

We report that phosphorylation of gasdermin D (GSDMD)-NT, cleaved by inflammatory caspases, could inhibit pyroptosis. Phosphatase 1 (PP1) is responsible for the regulation of GSDMD phosphorylation and the capacity of GSDMD to induce cell death. Our findings reveal a critical regulatory mechanism as it provides insight into pyroptosis processes.

Graphical abstract: Protein phosphatase 1 regulates phosphorylation of gasdermin D and pyroptosis

Page: ^ Top


Enter Keywords, author, title,reference, or DOI
Log in | Register