Direct biocatalysed synthesis of first sulfur-, selenium- and tellurium- containing L-ascorbyl hybrid derivatives with radical trapping and GPx-like properties

Damiano Tanini; Beatrice Lupori; Gianni Malevolti; Moira Ambrosi; Pierandrea Lo Nostro; Antonella Capperucci

doi:10.1039/C9CC02427A

This website uses cookies to give you the best user experience. If you continue without changing your settings we'll assume you are happy to receive all RSC cookies. You can change your cookie settings by navigating to our Privacy and Cookies page and following the instructions. These instructions are also obtainable from the privacy link at the bottom of any RSC page.

Lite Version|Standard version

Home > Chemical Communications > Direct biocatalysed syn...

Direct biocatalysed synthesis of first sulfur-, selenium- and tellurium- containing L-ascorbyl hybrid derivatives with radical trapping and GPx-like properties

Damiano Tanini, Beatrice Lupori, Gianni Malevolti, Moira Ambrosi, Pierandrea Lo Nostro and Antonella Capperucci
Chem. Commun., 2019,55, 5705-5708
DOI: 10.1039/C9CC02427A, Communication

Download

PDF

Rich HTML

Abstract | Cited by

6-O-L-Ascorbyl selenoesters, thioesters and telluroesters can be efficiently and directly prepared from L-ascorbic acid and suitable functionalised chalcogenoesters through lipase-catalysed transesterification reactions. Novel synthesised L-ascorbyl derivatives exhibited remarkable chain breaking and glutathione peroxidase-like activities.

Graphical abstract: Direct biocatalysed synthesis of first sulfur-, selenium- and tellurium- containing l-ascorbyl hybrid derivatives with radical trapping and GPx-like properties

Page: ^ Top

Terms & Conditions | Privacy and Cookies