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Development of photoacoustic (PA) imaging agents is crucial to advancing PA imaging in biology and medicine. In this study, we report the design and synthesis of near-infrared (NIR) absorbing amphiphilic semiconducting polymers that can spontaneously self-assemble into homogeneous water-soluble nanoparticles for PA imaging of tumor in living mice.

Graphical abstract: Near-infrared absorbing amphiphilic semiconducting polymers for photoacoustic imaging

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