New opportunities for cyclodextrins in supramolecular assembly: metal organic frameworks, crystalline self-assembly, and catalyzed assembly

Cyclodextrins (CDs) are widely used macrocycles in supramolecular assembly due to their easy availability, versatile functionality and excellent biocompatibility. Although they are well-known for forming host–guest complexes with a wide range of guests and this host–guest chemistry has long been utilized in industry and academia, new opportunities have arisen in recent years, particularly in supramolecular assembly. In the present review, we will first provide a basic introduction to CDs and then summarize their emerging roles in the fields of supramolecular chemistry and materials. This includes their involvement in hybrid frameworks with inorganic components such as metal ions and polyoxometalates, crystalline self-assembly with amphiphilic molecules, and their new possibility of “catassembly” and induced chiral supramolecular structures that have previously been overlooked. Finally, we will comment on the future perspectives of CDs to inspire more ideas and efforts, with the aim of promoting diverse applications of CDs in supramolecular materials.