Zhiming Cui, Baofu Zhu, Xuechen Li and Hua Cao
Org. Chem. Front., 2018,5, 2219-2223
DOI:
10.1039/C8QO00443A,
Research Article
An efficient three-component reaction of 1,3-dicarbonyl compounds or pyridin-2-amines with ynals and sodium benzenesulfinates has been developed. This domino process provides a new and effective strategy for the preparation of sulfonylated furan or imidazo[1,2-a]pyridine derivatives. The strategy exhibits excellent functional group tolerance and good efficiency.
![Graphical abstract: Access to sulfonylated furans or imidazo[1,2-a]pyridines via a metal-free three-component, domino reaction](/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=C8QO00443A "Graphical abstract")
