A convenient method for oxidant-promoted radical cascade acylation or decarbonylative alkylation of 1,7-dienes with aldehydes for the construction of tetracyclic N-containing skeletons has been established.
The C5 regioselective methoxylation and cyanomethoxylation of 8-aminoquinolines were achieved under FeIII/TBHP system by tuning the temperature and solvent. TBHP was investigated as an “oxygen” source in the ether bond formation for the first time.
Electron-withdrawing ligands increase epoxidation activity, but decrease oxyanion reduction catalysis.
A straightforward transition-metal-free sustainable methodology for oxidative cyclopropanation of aza-1,6-enynes has been devised, enabling the synthesis of valuable, functionalized azabicyclo[4.1.0]heptane-2,4,5-triones.
A paired electrolysis enabled amination of arenes using N,N-dialkyl formamides as the amine source for the synthesis of arylamines without the need for chemical oxidants, metal catalysts or high temperatures is reported.