Rapidly Degrading Hydrogels to Support Biofabrication and 3D Bioprinting Using Cartilage Microtissues

Gabriela S. Kronemberger, Francesca D. Spagnuolo, Aliaa S. Karam, Kaoutar Chattahy, Kyle J. Storey and Daniel J. Kelly

ACS Biomater. Sci. Eng., 2024, 10, 6441
DOI: 10.1021/acsbiomaterials.4c00819

Novel role of estrogen receptor-α on regulating chondrocyte phenotype and response to mechanical loading

N. Wang, X. Zhang, B.B. Rothrauff, M.R. Fritch, A. Chang, Y. He, M. Yeung, S. Liu, K.E. Lipa, G. Lei, P.G. Alexander and H. Lin

Osteoarthritis and Cartilage, 2022, 30, 302
DOI: 10.1016/j.joca.2021.11.002

Piezo1-ERK1/2-YAP Signaling Cascade Regulates the Proliferation of Urine-derived Stem Cells on Collagen Gels

Xiaoya Wang, Ling Li, Bishao Sun, Xianglin Hou, Siqi Song, Chunying Shi and Wei Chen

CSCR, 2024, 19, 103
DOI: 10.2174/1574888X18666230331123540

Advancements in hydrogel design for articular cartilage regeneration: A comprehensive review

Fariba Hashemi-Afzal, Hooman Fallahi, Fatemeh Bagheri, Maurice N. Collins, Mohamadreza Baghaban Eslaminejad and Hermann Seitz

Bioactive Materials, 2025, 43, 1
DOI: 10.1016/j.bioactmat.2024.09.005

Facile Preparation of Drug-Releasing Supramolecular Hydrogel for Preventing Postoperative Peritoneal Adhesion

Xianwen Song, Zequn Zhang, Zhaolong Shen, Jun Zheng, Xi Liu, Yaqiong Ni, Jun Quan, Xiaorong Li, Gui Hu and Yi Zhang

ACS Appl. Mater. Interfaces, 2021, 13, 56881
DOI: 10.1021/acsami.1c16269

Colonic TRPV4 overexpression is related to constipation severity

Hiroshi Mihara, Kunitoshi Uchida, Yoshiyuki Watanabe, Sohachi Nanjo, Miho Sakumura, Iori Motoo, Takayuki Ando, Masami Minemura, Jibran Sualeh Muhammad, Hiroyuki Yamamoto, Fumio Itoh and Ichiro Yasuda

BMC Gastroenterol, 2023, 23
DOI: 10.1186/s12876-023-02647-0

Double-edged role of mechanical stimuli and underlying mechanisms in cartilage tissue engineering

Yao Jia, Hanxiang Le, Xianggang Wang, Jiaxin Zhang, Yan Liu, Jiacheng Ding, Changjun Zheng and Fei Chang

Front. Bioeng. Biotechnol., 2023, 11
DOI: 10.3389/fbioe.2023.1271762

LIPUS regulates the progression of knee osteoarthritis in mice through primary cilia-mediated TRPV4 channels

Sha Wu, Haiqi Zhou, Huixian Ling, Yuyan Sun, Ziyu Luo, ThaiNamanh Ngo, Yuanyuan Fu, Wen Wang and Ying Kong

Apoptosis, 2024, 29, 785
DOI: 10.1007/s10495-024-01950-9

Engineered mechanical dynamics in biomimetic hydrogel scaffold promotes phenotypic maintenance and cartilage formation of chondrocytes

Yinghua Gao, Xuran Guo, Xiaoli Wang, Donghong Li, Han Tang, Weisong Zhao, Tingting Xu, Sha-sha Wang, Fen Li, Hao Zhang, Bei Feng and Yanzhong Zhang

Composites Part B: Engineering, 2024, 284, 111665
DOI: 10.1016/j.compositesb.2024.111665

Dynamic Mechanical Stimulation of Thermoresponsive Nanofibers for Activation of Fibroblasts in Skin Repair

Xuran Guo, Ying Gao, Jiajia Yu, Sha Qiu, Xiaoli Wang, Shasha Wang, Chunling Zhang, Bingcheng Yi and Yinghua Gao

Adv Healthcare Materials, 2025
DOI: 10.1002/adhm.202500277

An Advanced Mechanically Active Osteoarthritis‐on‐Chip Model to Test Injectable Therapeutic Formulations: The SYN321 Case Study

Cecilia Palma, Stefano Piazza, Roberta Visone, Rune Ringom, Ulf Björklund, Antonio Bermejo Gómez, Marco Rasponi and Paola Occhetta

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202401187

Biomimetic Hydrogels as the Inductive Endochondral Ossification Template for Promoting Bone Regeneration

Fujian Zhao, Yonghao Qiu, Wenjing Liu, Yanli Zhang, Jia Liu, Liming Bian and Longquan Shao

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202303532

In situ Hydrogels Prepared by Photo-initiated Crosslinking of Acrylated Polymers for Local Delivery of Antitumor Drugs

Yuandou Wang, Shuxin Wang, Wenju Hu, Shaowen Kong, Feng Su, Fusheng Liu and Suming Li

Journal of Pharmaceutical Sciences, 2023, 112, 1863
DOI: 10.1016/j.xphs.2023.02.004

The role of PIEZO ion channels in the musculoskeletal system

Alireza Savadipour, Daniel Palmer, Erica V. Ely, Kelsey H. Collins, Jaquelin M. Garcia-Castorena, Zainab Harissa, Yu Seon Kim, Arin Oestrich, Feini Qu, Neda Rashidi and Farshid Guilak

American Journal of Physiology-Cell Physiology, 2023, 324, C728
DOI: 10.1152/ajpcell.00544.2022

Drug delivery systems based on polyethylene glycol hydrogels for enhanced bone regeneration

Shouye Sun, Yutao Cui, Baoming Yuan, Minghan Dou, Gan Wang, Hang Xu, Jingwei Wang, Wen Yin, Dankai Wu and Chuangang Peng

Front. Bioeng. Biotechnol., 2023, 11
DOI: 10.3389/fbioe.2023.1117647

Mechanotransduction pathways in articular chondrocytes and the emerging role of estrogen receptor-α

Ning Wang, Yangfan Lu, Benjamin B. Rothrauff, Aojie Zheng, Alexander Lamb, Youzhen Yan, Katelyn E. Lipa, Guanghua Lei and Hang Lin

Bone Res, 2023, 11
DOI: 10.1038/s41413-023-00248-x

Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying MicroRNA-181c-5p Promote BMP2-Induced Repair of Cartilage Injury through Inhibition of SMAD7 Expression

Qiang Zhang, Le Cao, Shanqi Zou, Yuanling Feng, Xudong Miao, Lu Huang, Yongping Wu and Tong-Chuan He

Stem Cells International, 2022, 2022, 1
DOI: 10.1155/2022/1157498

Integrins, cadherins and channels in cartilage mechanotransduction: perspectives for future regeneration strategies

Martin Philipp Dieterle, Ayman Husari, Bernd Rolauffs, Thorsten Steinberg and Pascal Tomakidi

Expert Rev. Mol. Med., 2021, 23
DOI: 10.1017/erm.2021.16

Mechanobiological Approaches for Stimulating Chondrogenesis of Stem Cells

Mallory Volz, Kimberley R. Wyse-Sookoo, Francesco Travascio, Chun-Yuh Huang and Thomas M. Best

Stem Cells and Development, 2022, 31, 460
DOI: 10.1089/scd.2022.0049

Bioactive protein/polysaccharide hydrogel functionalized bone implants surface for enhanced osteogenesis

Hongyun Ma, Xiaochen Su, Jingqi Liang, Liang Liu, Jianbo Sun, Jin Tong, Jun Lu, Yingang Zhang, Bo Lei and Hongmou Zhao

International Journal of Biological Macromolecules, 2025, 317, 144626
DOI: 10.1016/j.ijbiomac.2025.144626