Issue 47, 2019

Hydrogenation and N-alkylation of anilines and imines via transfer hydrogenation with homogeneous nickel compounds

Abstract

The nickel-catalyzed N-alkylation of a variety of arylamines via transfer hydrogenation in the absence of pressurized hydrogen and basic or acidic additives was achieved in a tandem reaction. This process was further extended to the C[double bond, length as m-dash]N bond reduction and N-alkylation of a variety of imines with ethanol, the latter acting as a hydrogen and acetaldehyde source, which allowed for the reduction and subsequent condensation to yield the corresponding N-alkylated products.

Graphical abstract: Hydrogenation and N-alkylation of anilines and imines via transfer hydrogenation with homogeneous nickel compounds

Supplementary files

Article information

Article type
Paper
Submitted
21 Қаз. 2019
Accepted
07 Қар. 2019
First published
08 Қар. 2019

Dalton Trans., 2019,48, 17579-17587

Hydrogenation and N-alkylation of anilines and imines via transfer hydrogenation with homogeneous nickel compounds

G. E. Benitez-Medina and J. J. García, Dalton Trans., 2019, 48, 17579 DOI: 10.1039/C9DT04111G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements