Issue 28, 2024

Chiromagnetic Co(OH)2 nanoparticles with high asymmetry for electrochemical recognition and detection of ascorbic acid enantiomers

Abstract

L-ascorbic acid (L-AA) and its enantiomer D-isoascorbic acid (D-IAA) with similar physicochemical properties have been broadly used in healthcare, cosmetic, and food industries. However, L-AA shows much higher physiological activity than D-IAA in maintaining human health. Therefore, effective recognition and detection of L-AA and D-IAA is essential. Herein, chiromagnetic Co(OH)2 nanoparticles with tunable asymmetry g-factors ranging from 0.012 to 0.053 are synthesized by the coordination of d- or L-aspartic acid and used to recognize L-AA and D-IAA by an electrochemical method. Chiral Co(OH)2 catalysts have enantioselective electrochemical L-AA and D-IAA oxidation activities, and the oxidation of AA is easier to proceed on homochiral Co(OH)2 catalyst due to a smaller oxidization barrier and the chirality-induced spin selectivity effect. Moreover, the asymmetry of the Co(OH)2 catalyst strongly influences the oxidation of the homochiral AA reactant. According to the linear curves of oxidation current density versus AA concentration over the different chiral Co(OH)2 catalysts, recognizing the chirality and concentration of AA can be easily achieved. This electrochemical AA oxidation method can recognize AA at the nM level and is sensitive to changes in AA concentration, providing good application prospects.

Graphical abstract: Chiromagnetic Co(OH)2 nanoparticles with high asymmetry for electrochemical recognition and detection of ascorbic acid enantiomers

Supplementary files

Article information

Article type
Paper
Submitted
02 Сәу. 2024
Accepted
13 Мау. 2024
First published
14 Мау. 2024

J. Mater. Chem. A, 2024,12, 17277-17285

Chiromagnetic Co(OH)2 nanoparticles with high asymmetry for electrochemical recognition and detection of ascorbic acid enantiomers

D. Tian, J. Li, S. Qi, X. Liu, A. Zhi, X. Tian, B. Li, Z. Wang and Z. Lou, J. Mater. Chem. A, 2024, 12, 17277 DOI: 10.1039/D4TA02192D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements