Issue 78, 2018

Catalytic regeneration of a Th–H bond from a Th–O bond through a mild and chemoselective carbonyl hydroboration

Abstract

Here we present an unprecedented chemoselective hydroboration for aldehydes and ketones catalysed by actinides. The reaction features a very low catalyst loading (0.1–0.004 mol%) and quantitative product formation in less than 15 minutes, at room temperature. Thermodynamic and kinetic studies including stoichiometric and labeling studies with deuterated pinacolborane allow us to propose a plausible mechanism for this remarkable catalytic regeneration of a Th–H bond via carbonyl hydroboration.

Graphical abstract: Catalytic regeneration of a Th–H bond from a Th–O bond through a mild and chemoselective carbonyl hydroboration

Supplementary files

Article information

Article type
Communication
Submitted
26 Мау. 2018
Accepted
01 Қыр. 2018
First published
03 Қыр. 2018

Chem. Commun., 2018,54, 11001-11004

Catalytic regeneration of a Th–H bond from a Th–O bond through a mild and chemoselective carbonyl hydroboration

T. Ghatak, K. Makarov, N. Fridman and M. S. Eisen, Chem. Commun., 2018, 54, 11001 DOI: 10.1039/C8CC05030A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements