Issue 30, 2016
From the journal:

Journal of Materials Chemistry B

A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition†

Yutao Yang,‡ab   Fangjun Huo,‡b   Caixia Yin,*a   Ming Xu,c   Ying Hu,d   Jianbin Chao,b   Yongbin Zhang,b   Timothy E. Glass*c  and  Juyoung Yoon*d  

* Corresponding authors

a Institute of Molecular Science, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Shanxi University, Taiyuan 030-006, P. R. China
E-mail: yincx@sxu.edu.cn

b Research Institute of Applied Chemistry, Shanxi University, Taiyuan, China

c Department of Chemistry, University of Missouri 601 South College Avenue, Columbia, Missouri 65211, USA
E-mail: glasst@missouri.edu

d Department of Chemistry and Nano Science, Ewha Womans University, Seoul, Korea
E-mail: jyoon@ewha.ac.kr

Abstract

The reaction of salicylhydroxamic acid with hypochlorite produces 1,2-benzisoxazoline-3-one, a heterocycle that contains a fluorophore. As a result, this reaction was used as the basis for a new, selective and sensitive fluorescence system for the recognition of hypochlorite. The effectiveness of the method was demonstrated by its use to detect hypochlorite in a disinfectant solution as well as to image hypochlorite in cells.

Graphical abstract: A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition

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Article information

DOI
https://doi.org/10.1039/C6TB01392A
Article type
Communication
Submitted
04 Мау. 2016
Accepted
04 Шіл. 2016
First published
05 Шіл. 2016
This article is Open Access
Creative Commons BY-NC license

J. Mater. Chem. B, 2016,4, 5101-5104

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A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition

Y. Yang, F. Huo, C. Yin, M. Xu, Y. Hu, J. Chao, Y. Zhang, T. E. Glass and J. Yoon, J. Mater. Chem. B, 2016, 4, 5101 DOI: 10.1039/C6TB01392A

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