Issue 14, 2012

Regioselective synthesis of isocoumarins by ruthenium-catalyzed aerobic oxidative cyclization of aromatic acids with alkynes

Abstract

The highly regioselective aerobic oxidative cyclization of aromatic, heteroaromatic and alkenyl acids with alkynes in the presence of catalytic amounts of [{RuCl2(p-cymene)}2], AgSbF6 and Cu(OAc)2·H2O providing isocoumarin derivatives was investigated.

Graphical abstract: Regioselective synthesis of isocoumarins by ruthenium-catalyzed aerobic oxidative cyclization of aromatic acids with alkynes

Supplementary files

Article information

Article type
Communication
Submitted
08 Қар. 2011
Accepted
14 Жел. 2011
First published
14 Жел. 2011

Chem. Commun., 2012,48, 2030-2032

Regioselective synthesis of isocoumarins by ruthenium-catalyzed aerobic oxidative cyclization of aromatic acids with alkynes

R. K. Chinnagolla and M. Jeganmohan, Chem. Commun., 2012, 48, 2030 DOI: 10.1039/C2CC16916A

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