Issue 7, 2017

Surface-enhanced Raman spectroscopy and microfluidic platforms: challenges, solutions and potential applications

Abstract

The exhaustive body of literature published in the last four years on the development and application of systems based on surface-enhanced Raman spectroscopy (SERS) combined with microfluidic devices demonstrates that this research field is a current hot topic. This synergy, also referred to as lab-on-a-chip SERS (LoC-SERS) or nano/micro-optofluidics SERS, has opened the door for new opportunities where both techniques can profit. On the one hand, SERS measurements are considerably improved because the processes previously performed on a large scale in the laboratory and prone to human error can now be carried out in nanoliter volumes in an automatic and reproducible manner; on the other hand, microfluidic platforms need detection methods able to sense in small volumes and therefore, SERS is ideal for this task. The present review not only aims to provide the reader an overview of the recent developments and advancements in this field, but it also addresses the key aspects of fundamental SERS theory that influence the interpretation of SERS spectra, as well as the challenges brought about by the experimental conditions and chemometric data analysis.

Graphical abstract: Surface-enhanced Raman spectroscopy and microfluidic platforms: challenges, solutions and potential applications

Article information

Article type
Critical Review
Submitted
20 Қаң. 2017
Accepted
23 Ақп. 2017
First published
27 Ақп. 2017

Analyst, 2017,142, 1022-1047

Surface-enhanced Raman spectroscopy and microfluidic platforms: challenges, solutions and potential applications

I. J. Jahn, O. Žukovskaja, X.-S. Zheng, K. Weber, T. W. Bocklitz, D. Cialla-May and J. Popp, Analyst, 2017, 142, 1022 DOI: 10.1039/C7AN00118E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements