N-Acylurea, a notorious side product, poisons catalysts in the carbodiimide-fueled reaction cycles. This work tested how to suppress catalyst poisoning, providing guidelines for regulating molecular function and choosing an optimal condition.
We analyze the source of the residual line width in refocused homonuclear-decoupled spectra in detail by comparing numerical simulations and experimental data. We find that rf imperfections can severely limit the achievable decoupling performance.
In this study, the first highly chemoselective amidation of Boc and amide groups of N-R-N-Boc arylamides is advanced.
This paper describes a new analytical approach for determining gamma-hydroxybutyric acid (GHB) in biosamples using liquid chromatography-mass spectrometry (LC-MS) following derivatization with N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDC).
EDC-induced gelation of succinylated collagen with a high concentration was realized, and its triple helix structure is crucial for this process. G′ of succinylated collagen hydrogel was improved to 310 Pa compared to 20 Pa of the collagen hydrogel.