Progress in the treatment of Alzheimer's disease based on nanosized traditional Chinese medicines

Dan Song, Jieyu Zhang, Xuefeng Hu and Xiaoyan Liu

J. Mater. Chem. B, 2025, 13, 1548
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Traditional Chinese medicine as a promising choice for future control of PEDV

Conghao Ji, Shuxuan Li, Cunhai Hu, Tongtong Liu, Qingqing Huang, Mengyuan Yang, Mengxin Yang, Qianqian Wang, Aifang Li, Dandan Guo, Yu Huang, Sugai Yin and Shuying Feng

Virus Research, 2025, 356, 199572
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Advancements in herbal medicine-based nanozymes for biomedical applications

Mei Yang, Zhichao Deng, Yuanyuan Zhu, Chenxi Xu, Chenguang Ding, Yujie Zhang, Mingxin Zhang and Mingzhen Zhang

Chinese Medical Journal, 2025, 138, 1037
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Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

Ying‐qi Cao, Zheng‐ting Wu, Qi You, Yuan‐yuan Xia, Qing Zhao, Carine de Marcos Lousa and Ke‐wei Zhao

Interdisciplinary Medicine, 2025, 3
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De novo engineering of nanoformulation from traditional Chinese medicine mixtures for psoriasis

Yang Li, Dan Zhang, Tianzi Shi, Yulin Yu, Yinmei Tian, Qi Xie, Jingyu Shi, Li Kong, Conglian Yang and Zhiping Zhang

Nano Res., 2023, 16, 5279
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Herbal Medicine-Derived Exosome-Like Nanovesicles: A Rising Star in Cancer Therapy

Kaifei Chu, Jie Liu, Xu Zhang, Minran Wang, Wanping Yu, Yuyue Chen, Lingling Xu, Geng Yang, Naru Zhang and Tiejun Zhao

IJN, 2024, Volume 19, 7585
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Advanced Application of Polymer Nanocarriers in Delivery of Active Ingredients from Traditional Chinese Medicines

Zhiyuan Zhai, Jianda Niu, Liguo Xu and Jinbao Xu

Molecules, 2024, 29, 3520
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Enhancing flavonoid enrichment via supramolecular: A study on the material basis of Sanguisorbae radix after carbonizing by stir-frying

Feng Li, Hongdan Wu, Ruixiao Ma, Xuxi Cheng, Huiwen Yu, Xinxin Li, Xianqi Zhou, Jiarong Xu, Bohui Song, Qinglian Hu, Jing Ji, Huangjin Tong and Wei Gu

LWT, 2025, 215, 117192
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Nature Herbal Medicine‐ Tissue Engineering Strategies for Regulate Cell Homeostasis in Bone Regeneration

Xu Wei, Hao Xie, Can Liu, Yan Li, Kai Sun, Baoyu Qi, Xiangyun Guo, Zhaofeng Liu, Xinlin Huang, Chuanrui Sun, Jian Wang, Yili Zhang, Lei Fan and Liguo Zhu

Adv Funct Materials, 2025, 35
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Research progress on nanotechnology of traditional Chinese medicine to enhance the therapeutic effect of osteoarthritis

Yue Peng, Zhengshuang Yang, Jinling Li and Sijia Liu

Drug Deliv. and Transl. Res., 2024, 14, 1517
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Exploiting the nanotechnological approaches for traditional Chinese medicine in childhood rhinitis: A review of future perspectives

Yao Zhang, Haicheng Dong, Yu Zhu, Wenfei Wang and Xinyue Zhang

Nanotechnology Reviews, 2024, 13
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Traditional Chinese medicine targets on hepatic stellate cells for the treatment of hepatic fibrosis: A mechanistic review

Dengcheng Hui, Lu Liu, Yanqin Bian, Nisma L. B. Azami, Jingru Song, Yanping Huang and Mingyu Sun

Portal Hypertension & Cirrhosis, 2023, 2, 16
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Nanocarrier-Based Delivery of Arsenic Trioxide for Hepatocellular Carcinoma Therapy

Jiang Sun, Mengying Cheng, Tingxian Ye, Bin Li, Yinghui Wei, Hangsheng Zheng, Hongyue Zheng, Meiqi Zhou, Ji-Gang Piao and Fanzhu Li

Nanomedicine (Lond.), 2022, 17, 2037
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A comprehensive overview of triptolide utilizing nanotechnology and its potential applications in prostate diseases

Tongyin Yan, Yiao Wang, Zhiyan Hou, Pan Song, Puze Wang, Jinze Li, Jing Zheng and Dong Lv

Front. Pharmacol., 2025, 16
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Plant-derived secondary metabolites and nanotechnology: innovative strategies and emerging challenges in myocardial ischemia-reperfusion injury therapy

Wei Shi, Yang Xu, Jian Wei, Xiaoyu Zhang, Shuaijie Zhu, Heng Guo, Qihui Huang, Chuyao Qi, Tianfeng Hua, Yue Liu and Min Yang

Front. Pharmacol., 2025, 16
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Traditional Chinese Medicine-Based Nanoformulations for Enhanced Photothermal Therapy of Cancer

Lin Yu, Xueying Qin, Bing Liang and Jingjing Liu

ACS Biomater. Sci. Eng., 2025, 11, 694
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Molecular signaling pathways in doxorubicin-induced nephrotoxicity and potential therapeutic agents

Changxu Lu, Jinwen Wei, Can Gao, Mingli Sun, Dan Dong and Zhongyi Mu

International Immunopharmacology, 2025, 144, 113373
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Therapeutic and prophylactic effects of baicalin on Pneumocystis infection in immunosuppressed rats

Ting Xue, Weiqin Du, Chaofeng Liu, Wenjuan Dai, Lei Wang, Pengzhou Kong, Jia Xu and Lufeng Chen

Biomedicine & Pharmacotherapy, 2025, 189, 118323
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Nano-formulated delivery of active ingredients from traditional Chinese herbal medicines for cancer immunotherapy

Qi Shang, Wandong Liu, Faith Leslie, Jiapei Yang, Mingmei Guo, Mingjiao Sun, Guangji Zhang, Qiang Zhang and Feihu Wang

Acta Pharmaceutica Sinica B, 2024, 14, 1525
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Effects of nano-Rhodiola rosea combined with treadmill exercise on anti-exercise fatigue in rats

Jibing Wang, Guoyan Zhang, Duona Wang, Yuanyuan Yan and Qin Yang

Front. Nutr., 2024, 11
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Application of Pharmaceutical Nanotechnologies for Chinese Herbal Medicines in the Treatment of Pulmonary Diseases and Lung Cancer

Xiaoping Yang, Hongxin Niu, Wen Jiang, Wanpeng Yu and Wenqing Jiang

IJN, 2025, Volume 20, 10567
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Targeting ferroptosis unveils a new era for traditional Chinese medicine: a scientific metrology study

Siyang Cao, Yihao Wei, Yaohang Yue, Yingqi Chen, Shuai Liao, Aikang Li, Peng Liu, Ao Xiong and Hui Zeng

Front. Pharmacol., 2024, 15
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YiQiWenShen formula ameliorates myasthenia gravis through T follicular helper cells/T follicular regulatory cells immune rebalancing

Kaihua Rao

Am J Transl Res, 2025, 17, 6333
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Mogroside V reduced the excessive endoplasmic reticulum stress and mitigated the Ulcerative colitis induced by dextran sulfate sodium in mice

Yue-Rong Tan, Si-Yang Shen, Xin-Yi Li, Peng-Fei Yi, Ben-Dong Fu and Lu-Yuan Peng

J Transl Med, 2024, 22
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Current landscape of dyslipidemia-related randomized clinical trials registered on the International Clinical Trials Registry Platform

Ling Pei, Muzhen Su, Reyihannisha Yakeya, Zhaoqian Hu, Aikedan Abudurexiti, Xiaochan Lin, Hongmei Zhao, Gulisitan Abudourexiti, Abudulimu Sidike and Xiaoli Li

Front. Public Health, 2025, 13
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Multi-omics analysis reveals the mechanism of action of ophiopogonin D against pulmonary fibrosis

Shengchuan Bao, Ting Chen, Juan Chen, Jiaxiang Zhang, Guangjian Zhang, Yi Hui, Jingtao Li and Shuguang Yan

Phytomedicine, 2023, 121, 155078
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Clinical Efficacy of Endoscopic Retrograde Cholangiopancreatography Combined With Traditional Chinese Medicine Comprehensive Nursing in the Treatment of Biliary Tract Complications After Liver Transplantation

Yingjia Li

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Nanoliposomes Encapsulated Rapamycin/Resveratrol to Induce Apoptosis and Ferroptosis for Enhanced Colorectal Cancer Therapy

Menglei Jia, Xiaoxiao Tan, Zhongwen Yuan, Wenting Zhu and Pengke Yan

Journal of Pharmaceutical Sciences, 2024, 113, 2565
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Acidic Environment-Responsive Metal Organic Framework-Mediated Dihydroartemisinin Delivery for Triggering Production of Reactive Oxygen Species in Drug-Resistant Lung Cancer

Xiaojie Yan, Xueying Zhao, Mingde Fan, Wenfu Zheng, Guanxiong Zhu, Bin Li and Le Wang

IJN, 2024, Volume 19, 3847
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Acetylcholine Analog-Modified Albumin Nanoparticles for the Enhanced and Synchronous Brain Delivery of Saponin Components of Panax Notoginseng

Ying Yu, Li Yun Wang, Yan Chi Liu, Hao Cui, Cheng Yuan and Cheng Xiao Wang

Pharm Res, 2024, 41, 513
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Therapeutic potential of traditional Chinese medicine loaded nanocarriers in wound management: Current status and their future perspective

Jitendra Gupta, Devesh Kumar, Reena Gupta, Diksha Diwakar, Kumari Shanno, Arpan Kumar Tripathi, Akshay Kumar and Mohit Kumar

Pharmacological Research - Modern Chinese Medicine, 2025, 15, 100622
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Traditional Chinese Medicine Formulae QY305 Reducing Cutaneous Adverse Reaction and Diarrhea by its Nanostructure

Ya‐Li Zhang, Ya‐Lei Wang, Ke Yan, Haiyan Li, Xinyu Zhang, Julien Milon Essola, Chengcheng Ding, Kexin Chang, Guangchao Qing, Fuxue Zhang, Yan Tan, Tiantian Peng, Xu Wang, Miao Jiang, Xing‐Jie Liang and Qian Hua

Advanced Science, 2024, 11
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Exploring the therapeutic implications of natural compounds modulating apoptosis in vascular dementia

Guangcheng Zhong, Xinyue Wang, Qian Zhang, Xueying Zhang, Xiaoling Fang, Shuting Li, Yaru Pan, Yujie Ma, Xuejing Wang, Ting Wan and Qi Wang

Phytotherapy Research, 2024, 38, 5270
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Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines

Chong Qiu, Jun Zhe Zhang, Bo Wu, Cheng Chao Xu, Huan Huan Pang, Qing Chao Tu, Yu Qian Lu, Qiu Yan Guo, Fei Xia and Ji Gang Wang

J Nanobiotechnol, 2023, 21
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Novel nano-drug delivery system for natural products and their application

Li Huang, Xue-Hua Huang, Xi Yang, Jia-Qin Hu, Yi-Zhun Zhu, Pei-Yu Yan and Ying Xie

Pharmacological Research, 2024, 201, 107100
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Prevention and treatment of radiation injury by traditional Chinese medicine: A review

Lixue He, Shixing Edi, Jun Ma, Zilin Kong, Chunguang Dai, Linfang Huang, Rui Zeng and Kaijun Gou

Chinese Herbal Medicines, 2025, 17, 220
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Panax notoginseng saponins and acetylsalicylic acid co-delivered liposomes for targeted treatment of ischemic stroke

Hao Cui, Yanchi Liu, Ying Yu, Dong Lv, Sha Ma, Mingju Gao, Ye Yang, Cheng Yuan, Yuan Liu and Chengxiao Wang

International Journal of Pharmaceutics, 2024, 667, 124782
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Nanotherapeutic derived from multiple bioactive ingredients of natural products: A robust tool for the development of traditional medicine

Mingsheng Chen

Pharmacological Research - Modern Chinese Medicine, 2024, 10, 100349
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Research progress on nanoplatforms based delivery of traditional Chinese medicine against multi-drug resistance in breast cancer

Gangcui Li, Xianghui Duan, Yanan Zhou, Hong Wang, Wenlu He, Qin Sun, Fulan Zhao, Roman Spáčil, Wenjun Miao and Wei Ren

Phytomedicine, 2025, 146, 157097
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Research progress of traditional Chinese medicine as sensitizer in reversing chemoresistance of colorectal cancer

Xiang Lin, Xinyu Yang, Yushang Yang, Hangbin Zhang and Xuan Huang

Front. Oncol., 2023, 13
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An enhanced cardio-protective effect of nanoparticles loaded with active components from Polygonum orientale L. against isoproterenol-induced myocardial ischemia in rats

Jincheng Jing, Shumei Fang, Yueting Li, Wenting Liu, Cong Wang, Yanyu Lan, Yonglin Wang and Chang Yang

International Journal of Pharmaceutics, 2024, 655, 124047
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Smart Targeted Delivery Systems for Enhancing Antitumor Therapy of Active Ingredients in Traditional Chinese Medicine

Chenglong Kang, Jianwen Wang, Ruotong Li, Jianing Gong, Kuanrong Wang, Yuxin Wang, Zhenghua Wang, Ruzhe He and Fengyun Li

Molecules, 2023, 28, 5955
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Design, Synthesis, Formulation, and Bioevaluation of Trisubstituted Triazines as Highly Selective mTOR Inhibitors for the Treatment of Human Breast Cancer

Qiwen Sun, Yuxiu Chu, Nana Zhang, Rui Chen, Lili Wang, Jiangxia Wu, Yongxi Dong, Hongliang Li, Ling Wang, Lei Tang, Changyou Zhan and Ji-Quan Zhang

J. Med. Chem., 2024, 67, 7330
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Nanoparticle Delivery of Active Traditional Chinese Medicine Ingredients: A New Strategy for the Treatment of Liver Cancer

Miaodong Wang, Peichun Peng, Zeshan Chen and Xin Deng

CPB, 2023, 24, 1630
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A Powerful Tool in the Treatment of Myocardial Ischemia-Reperfusion Injury: Natural and Nanoscale Modified Small Extracellular Vesicles Derived from Mesenchymal Stem Cells

Zhou Zhou, Xuan Zhang, Shuai Wang, Xianliang Wang and Jingyuan Mao

IJN, 2023, Volume 18, 8099
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Nanocarriers based therapy and diagnosis of brain diseases: cross the blood-brain barrier

Lijun An, Jinwei Zhang, Xiaobo Wang, Yuanyuan Ge, Kunhui Sun, Junlin Dong, Ping Wang, Wei Li, Meifang Li, Xuelei Hu, Bing Wang and Xie-An Yu

Science and Technology of Advanced Materials, 2025
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Preparation of aripiprazole-poly(methyl vinyl ether-co-maleic anhydride) nanocomposites via supercritical antisolvent process for improved antidepression therapy

Lin-Fei Chen, Ying Chen, You-Yu Duan, Man-Man Zhang, Pei-Yao Xu, Ranjith Kumar Kankala, Shi-Bin Wang and Ai-Zheng Chen

Regenerative Biomaterials, 2022, 9
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Enhanced tumor suppression in colorectal cancer via berberine-loaded PEG-PLGA nanoparticles

Fei Shen, Yun-Sheng Zheng, Lan Dong, Ziyang Cao and Jie Cao

Front. Pharmacol., 2024, 15
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Traditional Chinese medicine-based drug delivery systems for anti-tumor therapies

Ling YANG, Yani WANG, Xietao YE, Qiaoming LIU, Ding QU and Yan CHEN

Chinese Journal of Natural Medicines, 2024, 22, 1177
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Formation of a traditional Chinese medicine self-assembly nanostrategy and its application in cancer: a promising treatment

Ju Huang, Yu Zhu, Hang Xiao, Jingwen Liu, Songtao Li, Qiao Zheng, Jianyuan Tang and Xiangrui Meng

Chin Med, 2023, 18
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Hyaluronic acid application strategies for plant bioactive component delivery: A review

Ailin Zhang, Jianchang Huang, Yutong Liu, Hexin Gong, Feng Guan, Weinan Li, Fengjuan Han and Yanhong Wang

International Journal of Biological Macromolecules, 2024, 282, 137129
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Nanoparticle-based Traditional Chinese Medicine for Immunotherapy in Gastrointestinal Tumors

Linjia Peng, Yanfeng Liang, Qiuli Zhang, Xiaonan Guo, Zixuan Gao and Daxiang Cui

Nano Biomedicine and Engineering, 2025, 17, 161
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Application of Composite Biomaterials from Chinese Herbal Medicine in the Field of Bone Tissue Engineering

Liqing Ke, Wenxiang Cheng and Peng Zhang

Processes, 2023, 11, 1620
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Exploiting Nanotechnology for Drug Delivery: Advancing the Anti-Cancer Effects of Autophagy-Modulating Compounds in Traditional Chinese Medicine

Zixian Liu, Tianming Lu, Ruoning Qian, Zian Wang, Ruogu Qi and Zhengguang Zhang

IJN, 2024, Volume 19, 2507
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Functionalized biomimetic nanoparticles loaded with salvianolic acid B for synergistic targeted triple-negative breast cancer treatment

Nuo Cheng, Qianqian Zhou, Zongfang Jia, Yang Mu, Sheng Zhang, Lei Wang and Yunna Chen

Materials Today Bio, 2025, 30, 101441
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Development of modern Chinese medicine guided by molecular compatibility theory

Lifeng Luo, Jieru Zhou, Xiaonan Liu, Yanyu Chen, Xiao Du, Lili Gao, Yunting Sun and Shuling Wang

Journal of Advanced Research, 2025, 73, 713
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The role of plant-derived extracellular vesicles in ameliorating chronic diseases

Ashwani Tiwari, Naveen Soni, Shweta Dongre, Megha Chaudhary and Bhawana Bissa

Mol Biol Rep, 2025, 52
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Mechanistic insights into pachymic acid’s action on triple-negative breast Cancer through TOP2A targeting

Ming Liu, Li Zheng, Yang Zhang and Jinhui Tian

Sci Rep, 2025, 15
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Unlocking the Medicinal Potential of Plant-Derived Extracellular Vesicles: current Progress and Future Perspectives

Xiaoliang Liu, Kecheng Lou, Yunmeng Zhang, Chuanxiao Li, Shenghong Wei and Shangzhi Feng

IJN, 2024, Volume 19, 4877
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Use of traditional Chinese medicine bezoars and bezoar-containing preparations in hepatocarcinoma

De-Hui Li, Qian-Er Wen, Rui-Qi Feng, Chang Qiao and Xiao-Tong Tian

World J Gastrointest Oncol, 2024, 16, 4770
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Luteolin and glycyrrhetinic exert cooperative effect on liver cancer by selfassembling into carrier-free nanostructures

Lanlan Zong, Yuxin Dai, Jiahao Xu, Chaofeng Qiao, Yao Qi, Chengyuan Ma, Hong Li, Xiaobin Pang and Xiaohui Pu

Chinese Chemical Letters, 2025, 36, 111325
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Carrier-free Chinese herbal small molecules self-assembly with 3D-porous crystal framework as a synergistic anti-AD agent

Rui Shen, Yuhong Chen, Xiangyu Li, Xi Wang, Aihong Yang and Xiaodi Kou

International Journal of Pharmaceutics, 2023, 630, 122458
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Modified ZIF-8 Nanoparticles for Targeted Metabolic Treatment of Acute Spinal Cord Injury

Sen Lin, Jingwen Cui, Xiang Li, Shurui Chen, Kai Gao and Xifan Mei

ACS Appl. Mater. Interfaces, 2024, 16, 14503
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Self-Assembly of Rhein and Matrine Nanoparticles for Enhanced Wound Healing

Xunxun Wu, Ranqing Zang, Yiting Qiu, Ni Yang, Meiyan Liu, Site Wei, Xianxiang Xu and Yong Diao

Molecules, 2024, 29, 3326
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Collision of herbal medicine and nanotechnology: a bibliometric analysis of herbal nanoparticles from 2004 to 2023

Sinan Ai, Yake Li, Huijuan Zheng, Meiling Zhang, Jiayin Tao, Weijing Liu, Liang Peng, Zhen Wang and Yaoxian Wang

J Nanobiotechnol, 2024, 22
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Black Phosphorus Nanosheet-Loaded Traditional Chinese Medicine Curcumin for Acute Rhinosinusitis Therapy and Its Mechanism

Yongze Liu, Lei He, Dingding Liu, Xuefeng Jiang, Feng Chen, Xiaofeng Ma, Saijie Song, Jun Zhang, Jian Shen and Xia Gao

ACS Appl. Nano Mater., 2024, 7, 17239
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Lithospermic acid etched ZIF-8 nanoparticles delays osteoarthritis progression by inhibiting inflammatory signaling pathways and rescuing mitochondrial damage

Yu Zhang, Qiqi Lou, Hao Lian, Ran Yang, Ruolin Cui, Leyang Wang, Bitao Ma, Lingli Hou, Lilun Jin and Weiran Teng

Materials Today Bio, 2025, 31, 101589
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Study on the Nanoaggregate Formation Mechanism and Antipyretic Effect of Maxing Shigan Decoction

Bingbing Zhao, Yanxu Zhang, Zhengmin Fan, Ziwei Lin, Lihong Wang, Hongteng Li, Haojie Zhen and Chunli Wu

ACS Omega, 2024, 9, 19311
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Integration of active ingredients from traditional Chinese medicine with nano-delivery systems for tumor immunotherapy

Hao Zheng, Yiquan Chen, Wei Luo, Shiqi Han, Mengjuan Sun, Min Lin, Chenghan Wu, Lili Gao, Tian Xie and Na Kong

J Nanobiotechnol, 2025, 23
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