Application of Enantioselective Sulfur Ylide Epoxidation to a Short Asymmetric Synthesis of Bedaquiline, a Potent Anti-Tuberculosis Drug

Maryam Bashir, Muhammad Arshad, Robina Begum and Varinder K. Aggarwal

Org. Lett., 2023, 25, 4281
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The Emerging Landscape of Tubercular Targets: A Medicinal Chemistry Approach

Baji Baba Shaik, Kimeshni Moodley, Safiyah Ghumran, Muhammad D. Bala, Parvesh Singh and Rajshekhar Karpoormath

Medicinal Research Reviews, 2025, 45, 1077
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Expanding the squaramide library as mycobacterial ATP synthase inhibitors: Innovative synthetic pathway and biological evaluation

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Bioorganic & Medicinal Chemistry, 2023, 95, 117504
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Discovery of Anti‐tubercular Analogues of Bedaquiline with Modified A‐, B‐ and C‐Ring Subunits

Lisa Barbaro, Gayathri Nagalingam, James A. Triccas, Lendl Tan, Nicholas P. West, Daniel L. Priebbenow and Jonathan B. Baell

ChemMedChem, 2023, 18
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Discovery and preclinical profile of sudapyridine (WX-081), a novel anti-tuberculosis agent

Zhigang Huang, Wei Luo, Deming Xu, Fengxun Guo, Meng Yang, Yusong Zhu, Liang Shen, Shuhui Chen, Dongdong Tang, Lei Li, Yongguo Li, Bin Wang, Scott G Franzblau and Charles Z. Ding

Bioorganic & Medicinal Chemistry Letters, 2022, 71, 128824
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An update on ATP synthase inhibitors: A unique target for drug development in M. tuberculosis

Lakshmi Mounika Kelam, Mushtaq Ahmad Wani and Devendra K. Dhaked

Progress in Biophysics and Molecular Biology, 2023, 180-181, 87
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Integrating structure-guided and fragment-based inhibitor design to combat bedaquiline resistant Mycobacterium tuberculosis : a molecular dynamics study

Alankar Roy, Prantik Banerjee, Ishani Paul, Ritam Ghosh and Sujay Ray

Journal of Biomolecular Structure and Dynamics, 2026, 44, 1475
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Revolutionizing tuberculosis treatment: Breakthroughs, challenges, and hope on the horizon

Martin Kufa, Vladimir Finger, Ondrej Kovar, Ondrej Soukup, Carilyn Torruellas, Jaroslav Roh and Jan Korabecny

Acta Pharmaceutica Sinica B, 2025, 15, 1311
DOI: 10.1016/j.apsb.2025.01.023

Mycobacterium tuberculosis F-ATP Synthase Inhibitors and Targets

Amaravadhi Harikishore and Gerhard Grüber

Antibiotics, 2024, 13, 1169
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