On-demand release of a selective MMP-13 blocker from an enzyme-responsive injectable hydrogel protects cartilage from degenerative progression in osteoarthritis

Himadri Shekhar Roy, Preethi Murugesan, Chirag Kulkarni, Malika Arora, Geet Kumar Nagar, Rajdeep Guha, Naibedya Chattopadhyay and Deepa Ghosh

J. Mater. Chem. B, 2024, 12, 5325
DOI: 10.1039/D3TB02871B

Bio-responsive and multi-modality imaging nanomedicine for osteoarthritis theranostics

Song Xue, Guangfeng Ruan, Jia Li, Henning Madry, Chao Zhang and Changhai Ding

Biomater. Sci., 2023, 11, 5095
DOI: 10.1039/D3BM00370A

Screening of poly-beta amino ester coated emulsion of ketorolac for cartilage delivery

Tahani Saeedi and Polina Prokopovich

J. Mater. Chem. B, 2024, 12, 5930
DOI: 10.1039/D4TB00313F

Multi-stimuli-responsive hydrogels and their medical applications

Ali Pourjavadi, Rozhin Heydarpour and Zahra Mazaheri Tehrani

New J. Chem., 2021, 45, 15705
DOI: 10.1039/D1NJ02260A

Poly-beta-amino-ester licofelone conjugates development for osteoarthritis treatment

Raed Alghamdi, Fabrizio Pertusati and Polina Prokopovich

RSC Adv., 2024, 14, 15
DOI: 10.1039/D3RA04967A

Poly beta amino ester coated emulsions of NSAIDs for cartilage treatment

Tahani Saeedi and Polina Prokopovich

J. Mater. Chem. B, 2021, 9, 5837
DOI: 10.1039/D1TB01024G

Recent advances in targeted drug delivery for treatment of osteoarthritis

Shikhar Mehta, Tengfei He and Ambika G. Bajpayee

Current Opinion in Rheumatology, 2021, 33, 94
DOI: 10.1097/BOR.0000000000000761

Synthesis and Characterization of Poly (β-amino Ester) and Applied PEGylated and Non-PEGylated Poly (β-amino ester)/Plasmid DNA Nanoparticles for Efficient Gene Delivery

Sajid Iqbal, Alessandro F. Martins, Muhammad Sohail, Jingjing Zhao, Qi Deng, Muhan Li and Zhongxi Zhao

Front. Pharmacol., 2022, 13
DOI: 10.3389/fphar.2022.854859

Targeted treatment for osteoarthritis: drugs and delivery system

Liwei Mao, Wei Wu, Miao Wang, Jianmin Guo, Hui Li, Shihua Zhang, Jiake Xu and Jun Zou

Drug Delivery, 2021, 28, 1861
DOI: 10.1080/10717544.2021.1971798

Amplify antimicrobial photo dynamic therapy efficacy with poly-beta-amino esters (PBAEs)

Stefano Perni, Emily C. Preedy and Polina Prokopovich

Sci Rep, 2021, 11
DOI: 10.1038/s41598-021-86773-3

Liposomal dexamethasone for intra-articular therapy: Functional strategies and clinical progress

Qing Yao, Yifei Yang, Miyun Hu, Yifan Qiu, Yannan Shi and Longfa Kou

Journal of Controlled Release, 2025, 385, 114040
DOI: 10.1016/j.jconrel.2025.114040

Polymer colloids as drug delivery systems for the treatment of arthritis

Tahani Saeedi, Hadil Faris Alotaibi and Polina Prokopovich

Advances in Colloid and Interface Science, 2020, 285, 102273
DOI: 10.1016/j.cis.2020.102273

Poly (β‐amino esters) based potential drug delivery and targeting polymer; an overview and perspectives (review)

Sajid Iqbal, Ying Qu, Zhonghua Dong, Jianxiong Zhao, Abdur Rauf Khan, Shams Rehman and Zhongxi Zhao

European Polymer Journal, 2020, 141, 110097
DOI: 10.1016/j.eurpolymj.2020.110097

The Role of Glucocorticoids in Inflammatory Diseases

Sybille D. Reichardt, Agathe Amouret, Chiara Muzzi, Sabine Vettorazzi, Jan P. Tuckermann, Fred Lühder and Holger M. Reichardt

Cells, 2021, 10, 2921
DOI: 10.3390/cells10112921

Nanodevices for deep cartilage penetration

Xiao-Ling Xu, Yan Xue, Jia-Ying Ding, Zhi-Heng Zhu, Xi-Chen Wu, Yong-Jia Song, Yue-Long Cao, Long-Guang Tang, Dao-Fang Ding and Jian-Guang Xu

Acta Biomaterialia, 2022, 154, 23
DOI: 10.1016/j.actbio.2022.10.007

Progress in the Preparation of Functional and (Bio)Degradable Polymers via Living Polymerizations

Si-Ting Lin, Chung-Chi Wang, Chi-Jung Chang, Yasuyuki Nakamura, Kun-Yi Andrew Lin and Chih-Feng Huang

IJMS, 2020, 21, 9581
DOI: 10.3390/ijms21249581

Early Cost-Effectiveness Analysis of Intra-articular Delivery of a PBAE-DEX Conjugate for Osteoarthritis in a UK Population

Stefano Perni, Swathika Subburaman and Polina Prokopovich

Clin Drug Investig, 2025, 45, 387
DOI: 10.1007/s40261-025-01446-7

Platelet-cloaked alginate-poly (β-amino ester) a novel platform bioinspired polyelectrolyte nanoparticle for targeted delivery of carboplatin in breast cancer: An in vitro/in vivo study

Aliakbar Akbari, Jaleh Varshosaz, Mohsen Minaiyan, Parisa Heydari, Ardeshir Talebi, Mehrnaz Salahi and Ali Jahanian Najafabadi

International Journal of Pharmaceutics, 2024, 665, 124720
DOI: 10.1016/j.ijpharm.2024.124720

Advanced polymer composites and polymer hybrids for cartilage tissue engineering

Shan Liu, Xiao Hu, Min He, Wei Liu, Dengfeng Zhou, Yang Li and Shuhao Qin

Polymer Composites, 2024, 45, 11560
DOI: 10.1002/pc.28646

Combination of anti-inflammatory therapy and RNA interference by light-inducible hybrid nanomedicine for osteoarthritis treatment

Li Qiao, Zhiyao Li, Bowen Li, Fu Zhang, Zhuo Yao, Chongzhi Wu, Honglin Tang, Qi Pan, Peihua Shi and Yuan Ping

Acta Pharmaceutica Sinica B, 2024, 14, 5008
DOI: 10.1016/j.apsb.2024.06.009

Feasibility and application of machine learning enabled fast screening of poly-beta-amino-esters for cartilage therapies

Stefano Perni and Polina Prokopovich

Sci Rep, 2022, 12
DOI: 10.1038/s41598-022-18332-3

Molecular treatments to reduce catabolic effects in human meniscus explant models

Amanda Sjögren, Karin Lindblom, Aleksandra Turkiewicz, Martin Englund and Patrik Önnerfjord

Osteoarthritis and Cartilage Open, 2025, 7, 100618
DOI: 10.1016/j.ocarto.2025.100618