Towards practical and sustainable SERS: a review of recent developments in the construction of multifunctional enhancing substrates

Chunchun Li, Yiming Huang, Xinyuan Li, Yingrui Zhang, Qinglu Chen, Ziwei Ye, Zarah Alqarni, Steven E. J. Bell and Yikai Xu

J. Mater. Chem. C, 2021, 9, 11517
DOI: 10.1039/D1TC02134F

Hybridizing aggregated gold nanoparticles with a hydrogel to prepare a flexible SERS chip for detecting organophosphorus pesticides

Jiaxin Zhang, Xiajun Zhu, Mingming Chen, Tianwen Chen, Zhihong Liu, Jianli Huang, Fengfu Fu, Zhenyu Lin and Yongqiang Dong

Analyst, 2022, 147, 2802
DOI: 10.1039/D2AN00541G

Amino-induced cleavage of the electron-communicating S-bridge to unlock mixed-valence copper for potent oxidase-like catalysis and selective sensing

Bojin Li, Nannan Xia, Chaofeng Huang, Xun Hu and Fei He

Chem. Sci., 2025, 16, 14793
DOI: 10.1039/D5SC03521J

Place & Play SERS: sample collection and preparation-free surface-enhanced Raman spectroscopy

Yasutaka Kitahama, Pablo Martinez Pancorbo, Hiroki Segawa, Machiko Marumi, Ting-Hui Xiao, Kotaro Hiramatsu, William Yang and Keisuke Goda

Anal. Methods, 2023, 15, 1028
DOI: 10.1039/D2AY02090D

Facile fabrication of a large-area and cost-effective PDMS-SERS substrate by sandpaper template-assisted lithography

Ji Sun, Lin Gong, Zhengjun Gong, Dongmei Wang, Xiaosi Yin and Meikun Fan

Anal. Methods, 2019, 11, 4917
DOI: 10.1039/C9AY01494B

Halogen ion modified Ag NPs for ultrasensitive SERS detection of nitroaromatic explosives

Dongmei Wang, Zhengjun Gong, Mi Tang, Wanli Fan, Bing Huang and Meikun Fan

Anal. Methods, 2022, 14, 3798
DOI: 10.1039/D2AY01299E

Polydopamine-Assisted In Situ Growth of AgNPs on Face Masks for the Detection of Pesticide Based on Surface-Enhanced Raman Scattering Spectroscopy

Tongtong Wang, Qijia Zhang, Jia Li, Guangda Xu, Na Guo, Peng Song and Lixin Xia

Plasmonics, 2022, 17, 1743
DOI: 10.1007/s11468-022-01661-4

Highly sensitive bromide aided SERS detection of furazolidone and 3-amino-2-oxazolidinone residual in aquaculture products

Wanli Fan, Shiwei Yang, Weixing Gao, Dongmei Wang and Meikun Fan

Microchemical Journal, 2021, 169, 106532
DOI: 10.1016/j.microc.2021.106532

Developing a magnetic SERS nanosensor utilizing aminated Fe-Based MOF for ultrasensitive trace detection of organophosphorus pesticides in apple juice

Nengjing Yang, Hongbin Pu and Da-Wen Sun

Food Chemistry, 2024, 446, 138846
DOI: 10.1016/j.foodchem.2024.138846

Multiple Kinds of Pesticides Detection Based on Back-Propagation Neural Network Analysis of Fluorescence Spectra

Haiyi Bian, Hua Yao, Guohua Lin, Yinshan Yu, Ruiqiang Chen, Xiaoyan Wang, Rendong Ji, Xiao Yang, Tiezhu Zhu and Yongfeng Ju

IEEE Photonics J., 2020, 12, 1
DOI: 10.1109/JPHOT.2020.2973653

Assessing the effect of different pH maintenance situations on bacterial SERS spectra

Linbo Wei, Wen Liu, Chengye Zhu, Dongmei Wang, Zhengjun Gong and Meikun Fan

Anal Bioanal Chem, 2022, 414, 4977
DOI: 10.1007/s00216-022-04125-0

SERS detection of triazole pesticide residues on vegetables and fruits using Au decahedral nanoparticles

Zhinan Chen, Rui Tan, Mei Zeng, Xue Yuan, Kaiyi Zhuang, Changsheng Feng, Yi He and Xiaojun Luo

Food Chemistry, 2024, 439, 138110
DOI: 10.1016/j.foodchem.2023.138110

A SERS aptasensor for simultaneous multiple pathogens detection using gold decorated PDMS substrate

Nuo Duan, Mofei Shen, Shuo Qi, Wenyue Wang, Shijia Wu and Zhouping Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 230, 118103
DOI: 10.1016/j.saa.2020.118103

Rapid simultaneous adsorption and SERS detection of acid orange II using versatile gold nanoparticles decorated NH2-MIL-101(Cr)

Qinzhi Wang, Zhan Shi, Zhi Wang, Yijian Zhao, Jianuo Li, Huifan Hu, Yaowen Bai, Zhihao Xu, Hui Zhangsun and Li Wang

Analytica Chimica Acta, 2020, 1129, 126
DOI: 10.1016/j.aca.2020.07.015

Construction of pure worm-like AuAg nanochains for ultrasensitive SERS detection of pesticide residues on apple surfaces

Anxin Jiao, Xuejian Dong, Hua Zhang, Linlin Xu, Yue Tian, Xiangdong Liu and Ming Chen

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2019, 209, 241
DOI: 10.1016/j.saa.2018.10.051

Detection of thiram on fruit surfaces and in juices with minimum sample pretreatment via a bendable and reusable substrate for surface‐enhanced Raman scattering

Jiaqi Wu, Yiqun Huang, Junjian Miao and Keqiang Lai

J Sci Food Agric, 2022, 102, 6211
DOI: 10.1002/jsfa.11970

Boosting bacteria differentiation efficiency with multidimensional surface‐enhanced Raman scattering: the example of Bacillus cereus

Chengye Zhu, Wen Liu, Dongmei Wang, Zhengjun Gong and Meikun Fan

Luminescence, 2022, 37, 1145
DOI: 10.1002/bio.4268

Smart polydimethylsiloxane sponges with high piezoelectric responses

Hang Hu

Polymer Engineering & Sci, 2022, 62, 3964
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A covalently cross‐linked microporous polymer based micro‐solid phase extraction for online analysis of trace pesticide residues in citrus fruits

Tianfu Wei, Gongke Li and Zhuomin Zhang

J of Separation Science, 2019, 42, 888
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Carbon nanomaterials for the detection of pesticide residues in food: A review

Smriti Mishra, Shivangi Mishra, Shiv Singh Patel, Sheelendra Pratap Singh, Pradip Kumar, Mohd Akram Khan, Himani Awasthi and Shiv Singh

Environmental Pollution, 2022, 310, 119804
DOI: 10.1016/j.envpol.2022.119804

Multifunctional Flexible SERS Sensor on a Fixate Gel Pad: Capturing, Derivation, and Selective Picogram Indirect Detection of Explosive 2,2′,4,4′,6,6′-Hexanitrostilbene

Wanli Fan, Shiwei Yang, Yongzheng Zhang, Bing Huang, Zhengjun Gong, Dongmei Wang and Meikun Fan

ACS Sens., 2020, 5, 3599
DOI: 10.1021/acssensors.0c01908

One‐step synthesis of a spongy flexible substrate for surface enhanced Raman spectroscopy comprising a silver nanoparticles‐loaded poly(amidoamine) dendrimer crosslinked with glutaraldehyde

Juncheng Shen, Yingxin Wu, Juzhen Yi, Kainan Hong, Lin Yin, Xinye Ma and Liqun Yang

Journal of Polymer Science, 2024, 62, 4377
DOI: 10.1002/pol.20240094

Surface-enhanced Raman Scattering (SERS) microbial sensor for fresh water acute toxicity monitoring

Weixing Gao, Weiman Duan, Dandan Peng, Juan Li, Zhangmei Hu, Dongmei Wang, Zhengjun Gong and Meikun Fan

Microchemical Journal, 2023, 191, 108822
DOI: 10.1016/j.microc.2023.108822

Toward Flexible Surface‐Enhanced Raman Scattering (SERS) Sensors for Point‐of‐Care Diagnostics

Kaichen Xu, Rui Zhou, Kuniharu Takei and Minghui Hong

Advanced Science, 2019, 6
DOI: 10.1002/advs.201900925

A New Strategy for Direct Electrochemical Sensing of a Organophosphorus Pesticide, Triazophos, Using a Coomassie Brilliant-Blue Dye Surface-Confined Carbon-Black-Nanoparticle-Modified Electrode

K. S. Shalini Devi, Natarajan Anusha, Sudhakaran Raja and Annamalai Senthil Kumar

ACS Appl. Nano Mater., 2018, 1, 4110
DOI: 10.1021/acsanm.8b00861

Rapid field trace detection of pesticide residue in food based on surface-enhanced Raman spectroscopy

De Zhang, Pei Liang, Wenwen Chen, Zhexiang Tang, Chen Li, Kunyue Xiao, Shangzhong Jin, Dejiang Ni and Zhi Yu

Microchim Acta, 2021, 188
DOI: 10.1007/s00604-021-05025-3

Electrostatic and Capillary Force-Enhanced Dynamic SERS Combined with Machine Learning for Rapid Quantification of Structurally Similar Triazole Pesticides in Tobacco

Xinyue He, Shengmao Chao, Shana Zhou, RuiJuan Zhao, Chiara Valsecchi, Yechun Lin, Hui Yang and Meikun Fan

ACS Agric. Sci. Technol., 2025, 5, 414
DOI: 10.1021/acsagscitech.4c00757

Rapid and fingerprinted monitoring of pesticide methyl parathion on the surface of fruits/leaves as well as in surface water enabled by gold nanorods based casting-and-sensing SERS platform

Huixiang Wu, Yi Luo, Changjun Hou, Danqun Huo, Weilu Wang, Jing Zhao and Yu Lei

Talanta, 2019, 200, 84
DOI: 10.1016/j.talanta.2019.03.004

Polyvinyl Alcohol (PVA)/Nb 2 C/Ag Flexible Surface Enhanced Raman Spectroscopy (SERS) Substrate for Sensitive Determination of Phosmet Residues on Apple Surfaces

Denghao Li, Changqing Huang, Bo Yu, Dingyu Cui, Jiali Liu and Li Jiang

Analytical Letters, 2025, 1
DOI: 10.1080/00032719.2025.2511885

Factors that Affect Quantification in Surface-Enhanced Raman Scattering

Meikun Fan and Alexandre G. Brolo

ACS Nano, 2025, 19, 3969
DOI: 10.1021/acsnano.4c15183

Silver Nanoparticles-Loaded Cross-Linking Branched Polyethylenimine as a Spongy Flexible Substrate for Surface-Enhanced Raman Spectroscopy

Juncheng Shen, Yingxin Wu, Ju-Zhen Yi, Kainan Hong, Lin Yin, Xinye Ma and Liqun Yang

ACS Appl. Polym. Mater., 2024, 6, 7113
DOI: 10.1021/acsapm.4c00903

An anti-scratch flexible SERS substrate for pesticide residue detection on the surface of fruits and vegetables

Tianxun Gong, Haonan Li, Guilin Wang, Fang Guan, Wen Huang and Xiaosheng Zhang

Nanotechnology, 2022, 33, 405501
DOI: 10.1088/1361-6528/ac7cf3

Fabrication of Flexible AgNW@R-PDMS SERS Substrates by Sandpaper-Assisted Lithography for Surface Swab Capture of Fungicides

Aiswarya Mohan, Lekshmi Chandran and Kunnel Gopalan Gopchandran

ACS Appl. Opt. Mater., 2024, 2, 574
DOI: 10.1021/acsaom.4c00006

Application of surface-enhanced Raman spectroscopy using silver and gold nanoparticles for the detection of pesticides in fruit and fruit juice

Su-Yan Wang, Xin-Chi Shi, Gui-Yang Zhu, Yun-Jiao Zhang, Da-Yong Jin, Yi-Dong Zhou, Feng-Quan Liu and Pedro Laborda

Trends in Food Science & Technology, 2021, 116, 583
DOI: 10.1016/j.tifs.2021.08.006

A review on recent advances in the applications of surface-enhanced Raman scattering in analytical chemistry

Meikun Fan, Gustavo F.S. Andrade and Alexandre G. Brolo

Analytica Chimica Acta, 2020, 1097, 1
DOI: 10.1016/j.aca.2019.11.049

A Robust, Uniform, and Stable Glycerol Liquid Film Substrate for In Situ SERS Quantitative Investigation of Contaminant Distribution on Rough Surfaces

Dandan Peng, Xinyue He, Zhangmei Hu, Jacson Weber de Menezes, Chiara Valsecchi and Meikun Fan

Adv Materials Technologies, 2025, 10
DOI: 10.1002/admt.202400912

Sensitive surface-enhanced Raman scattering detection of atrazine based on aggregation of silver nanoparticles modified carbon dots

Jianshe Tang, Weiwei Chen and Huanxian Ju

Talanta, 2019, 201, 46
DOI: 10.1016/j.talanta.2019.03.108

Preparation of Fe3O4@UiO-66(Zr)@Ag NPs core-shell-satellite structured SERS substrate for trace detection of organophosphorus pesticides residues

Mingchun Lv, Hongbin Pu and Da-Wen Sun

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 294, 122548
DOI: 10.1016/j.saa.2023.122548

Free-Standing Membrane Liquid-State Platform for SERS-Based Determination of Norfloxacin in Environmental Samples

Jing Liu, Wen Liu, Sha-Na Zhou, Dong-Mei Wang, Zheng-Jun Gong and Mei-Kun Fan

J. Anal. Test., 2021, 5, 217
DOI: 10.1007/s41664-021-00192-x

A tailored dual core-shell magnetic SERS substrate with precise shell-thickness control for trace organophosphorus pesticides residues detection

Mingchun Lv, Hongbin Pu and Da-Wen Sun

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 316, 124336
DOI: 10.1016/j.saa.2024.124336

Preparation of Hydrophobic Film by Electrospinning for Rapid SERS Detection of Trace Triazophos

Fei Shao, Jiaying Cao, Ye Ying, Ying Liu, Dan Wang, Xiaoyu Guo, Yiping Wu, Ying Wen and Haifeng Yang

Sensors, 2020, 20, 4120
DOI: 10.3390/s20154120

One-pot platform for the collection and detection of nanoparticles: Flexible surface-enhanced Raman scattering (SERS) substrates with nano-pore structure

Seung Mo Kong, Dongha Shin, Jeong-Wook Oh, Hyungseok Park, Jea Seung Lee, Nam-Il Won and Yang Ho Na

Chemical Engineering Journal, 2023, 471, 144753
DOI: 10.1016/j.cej.2023.144753

Silver-Surface-Enhanced Raman Spectra of Berberine: Analyte-Induced Surface Changes, Variable Concentration Correlation, and Excitation Wavelength Dependence

Ivan Kopal and Valerie Smeliková

Langmuir, 2025, 41, 16725
DOI: 10.1021/acs.langmuir.4c05174

Transparent and flexible AuNSs/PDMS-based SERS substrates for in-situ detection of pesticide residues

Xiaoyuan Ma, Jie Xie, Zhouping Wang and Yin Zhang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 267, 120542
DOI: 10.1016/j.saa.2021.120542

Unsupported liquid-state platform for SERS-based determination of triazophos

Wen Liu, Yuting Huang, Jing Liu, Shengmao Chao, Dongmei Wang, Zhengjun Gong, Zhe Feng and Meikun Fan

Microchim Acta, 2020, 187
DOI: 10.1007/s00604-020-04474-6

Flexible SERS substrates for hazardous materials detection: recent advances

Moram Sree Satya Bharati and Venugopal Rao Soma

OEA, 2021, 4, 210048
DOI: 10.29026/oea.2021.210048

Molecular (Raman, NIR, and FTIR) spectroscopy and multivariate analysis in consumable products analysis1

Sayo O. Fakayode, Gary A. Baker, David K. Bwambok, Nakara Bhawawet, Brianda Elzey, Noureen Siraj, Samantha Macchi, David A. Pollard, Rocio L. Perez, A'ja V. Duncan and Isiah M. Warner

Applied Spectroscopy Reviews, 2020, 55, 647
DOI: 10.1080/05704928.2019.1631176

Self-supporting liquid film as reproducible SERS platform for therapeutic drug monitoring of berberine hydrochloride in human urine

Jing Liu, Wen Liu, Yuting Huang, Xin Zhao, Zhe Feng, Dongmei Wang, Zhengjun Gong and Meikun Fan

Microchemical Journal, 2021, 165, 106122
DOI: 10.1016/j.microc.2021.106122

A Performance-Enhanced Liquid Metal-Based Microheater with Parallel Ventilating Side-Channels

Lunjia Zhang, Pan Zhang, Ronghang Wang, Renchang Zhang, Zhenming Li, Wei Liu, Qifu Wang, Meng Gao and Lin Gui

Micromachines, 2020, 11, 133
DOI: 10.3390/mi11020133

Identification and Analysis of the Intermediates from Photodegradation of 3,3′-diamino-4,4′-azoxyfurazan (DAAF) by SERS and HPLC–MS/MS

Qi Wu, Zhenqi Zhang, Wenxu Zheng, Juan Li, Nan Ma, Rui Li, Bo Yang, Weimiao Wang, Xiaodong Li and Meikun Fan

J. Anal. Test., 2024, 8, 351
DOI: 10.1007/s41664-024-00303-4

Self-Assembly of Au–Ag Alloy Hollow Nanochains for Enhanced Plasmon-Driven Surface-Enhanced Raman Scattering

Weiyan Liu, Jianwen Zhang, Juan Hou, Haibibu Aziguli, Qiming Zhang and Hu Jiang

Nanomaterials, 2022, 12, 1244
DOI: 10.3390/nano12081244

Surface‐enhanced Raman spectroscopy for on‐site analysis: A review of recent developments

Ji Sun, Lin Gong, Wenjun Wang, Zhengjun Gong, Dongmei Wang and Meikun Fan

Luminescence, 2020, 35, 808
DOI: 10.1002/bio.3796

Recent Advances in Agglomeration Detection and Dual-Function Application of Surface-Enhanced Raman Scattering (SERS)

Bailin Dai, Yue Xu, Tao Wang, Shasha Wang, Li Tang and Jianxin Tang

j biomed nanotechnol, 2022, 18, 1257
DOI: 10.1166/jbn.2022.3356

Label-Free Surface-Enhanced Raman Scattering-Based Microbial Whole-Cell Biosensor for Acute Toxicity Assessment in Water

Nan Ma, Sijia Liu, Shana Zhou, Dongmei Wang, Zhengjun Gong and Meikun Fan

ACS EST Water, 2024, 4, 2204
DOI: 10.1021/acsestwater.3c00837

Label-free detection of pathogenic microorganism using Ag NPs@PDMS sponge SERS substrate and machine learning

Morui Wang, Haoxuan Diao, Cheng Dou, Zhenye Wu, Liguang Ruan, Zhixin Wang, Zhong Wang, Weichun Ye, Jiangong Duan and Yuee Li

Sensors and Actuators B: Chemical, 2024, 413, 135811
DOI: 10.1016/j.snb.2024.135811

State of the art in flexible SERS sensors toward label-free and onsite detection: from design to applications

Liping Xie, Hedele Zeng, Jiaxin Zhu, Zelin Zhang, Hong-bin Sun, Wen Xia and Yanan Du

Nano Res., 2022, 15, 4374
DOI: 10.1007/s12274-021-4017-4

Preparation of magnetic metal organic framework: A magnetically induced improvement effect for detection of parathion-methyl

Anni Zhu, Tong Xuan, Yan Zhai, Yiping Wu, Xiaoyu Guo, Ye Ying, Ying Wen and Haifeng Yang

Sensors and Actuators B: Chemical, 2021, 339, 129909
DOI: 10.1016/j.snb.2021.129909

High-performance SERS detection of pesticides using BiOCl-BiOBr@Pt/Au hybrid nanostructures on styrofoams as 3D functional substrate

Ramachandran Balaji, Renganathan Vengudusamy, Shen-Ming Chen, Tse-Wei Chen, Xiaoheng Liu, Mohammad Rizwan Khan, Zeid A. ALOthman, Mohammad Ajmal Ali and Saikh Mohammad Wabaidur

Microchim Acta, 2020, 187
DOI: 10.1007/s00604-020-04558-3

Durable and flexible Ag-nanowire-embedded PDMS films for the recyclable swabbing detection of malachite green residue in fruits and fingerprints

Juanjuan Luo, Zekai Wang, Yun Li, Changding Wang, Jiefang Sun, Weichun Ye, Xiaolong Wang and Bing Shao

Sensors and Actuators B: Chemical, 2021, 347, 130602
DOI: 10.1016/j.snb.2021.130602