Molecular conductance of double-stranded DNA evaluated by electrochemical capacitance spectroscopy

Abstract

Conductance was measured in two different double stranded DNA (both with 20 bases), the more conducting poly(dG)–poly(dC) (ds-DNAc) and the less conducting poly(dA)–poly(dT) (ds-DNAi), by means of Electrochemical Capacitance Spectroscopy (ECS). The use of the ECS approach, exemplified herein with DNA nanowires, is equally a suitable and time-dependent advantageous alternative for conductance measurement of molecular systems, additionally allowing better understanding of the alignment existing between molecular scale conductance and electron transfer rate.