The new pseudo-indoxyl compounds were synthesized by a designed simple metal-free methodology, and the lead compound 11f showed potent MAO-B inhibitory activity.
Asymmetric synthesis of 2,2-disubstituted indolin-3-ones has attracted much attention due to their presence in many important compounds. Herein, we discuss this unit's current state of asymmetric synthetic methods under different catalytic systems.
This paper reviews the structure, biosynthesis, synthesis, and activity of corynanthe alkaloids with the aim of providing new perspectives and discoveries for researchers in this field.
A divergent synthesis of heterohexacyclic derivatives via a silver or gold-catalyzed cascade cycloisomerization/[3 + 2] or [2 + 2 + 1] cycloaddition in HFIP.
The present review highlights the dearomatization of indoles by oxidizing C–H bonds for constructing oxindoles skeletons. Various synthetic approaches have been summarized followed by their applications in indole alkaloids and bioactive compounds.